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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Human GDF-15 Protein (Fc Tag)
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
20.00 µg/50.00 µg
| 规格: | 20.00 µg | 产品价格: | ¥1080.0 |
|---|---|---|---|
| 规格: | 50.00 µg | 产品价格: | ¥1980.0 |
蛋白名称:GDF15蛋白, GDF15 protein
蛋白构建:A DNA sequence encoding the mature form of human GDF15 (P01857.1) (Ala 197-Ile 308) was expressed with the fused Fc region of human IgG1 at the N-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 95 % as determined by SDS-PAGE
蛋白活性:0
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Glu 20
蛋白分子量:The recombinant human Fc/GDF15 is a disulfide-linked homodimeric protein. The reduced monomer consists of 370 amino acids and has a predicted molecular mass of 40.6 kDa. rhGDF15/Fc monomer migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions.
蛋白NP号:P01857.1
蛋白氨基酸序列:Ala197-Ile308
蛋白标签:N-human IgG1-Fc
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验1 月内连登 4 顶刊,这个炙手可热的明星蛋白 GDF15 到底什么来路?
1 月 9 号,代谢领域顶级期刊 Cell Metabolism 背靠背发表了题为《Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention》1 和《GDF15 Induces Anorexia through Nausea and Emesis》2 两篇长文,分别报道了 GDF15 在一型糖尿病和厌食症中的关键
三句话读懂一篇 CNS:颜宁团队 2023 首个研究成果发表;长期单身,患老年痴呆风险更高
agonist reduces body weight and metabolic disorder in mice and non-human primates。 该研究进行了长效双 GLP-1/GDF15 蛋白的设计和生成,发现了主要候选 GLP-1/GDF15 分子——QL1005,其在肥胖小鼠体内表现出较强的减肥效果,并对其他几种代谢结果进行有益的调节,以及改善药代动力学(PK)参数。 图 6:来源 Cell Metabolism 7. Journal of Hepatology:鉴定肝细胞
15 秒止血!MIT 赵选贺团队受自然启发,研制出如此神奇的
by barnacle glue. Nat Biomed Eng (2021).2. Sharma, B. et al. Human cartilage repair with a photoreactive adhesive–hydrogel composite. Sci. Transl. Med. 5, 167ra6 (2013).3. Annabi, N. et al. Engineering a highly elastic human protein-based sealant for surgical
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