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文献和实验Thioredoxins (Trx) are a ubiquitous family of proteins that modulate the enzymatic activity of their substrate proteins by redox regulation. This is achieved by reduction of a disulfide bond within their target proteins. A conserved pair
Thioredoxin and Redox Regulation of the Nuclear Receptor
Oxidative stress evokes various cellular responses including alteration of gene expression to preserve cellular homeostasis (1 ,2 ). Thioredoxin (TRX) is a small ubiquitous protein with protein thiol-reducing activity and has been shown
硫氧还蛋白还原酶 thioredoxin reductase
由还原型 NADP催化硫氧还蛋白还原的酶。 EC1. 6. 4. 5.。含有一个分子的 FAD。使氧化型硫氧还蛋白的胱氨酸残基还原,变成一对半胱氨酸残基,后者进一步成为核糖核苷酸还原的电子供体。它存在于大肠杆菌、酵母、肝脏以及肿瘤细胞中。
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