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文献和实验Purification of the Constitutive Nitric Oxide Synthase
Constitutive nitric oxide synthase (NOS) exists as two isoforms: endothelial (e) and neuronal (n) (reviewed in ref. 1 ). The first reports on the purification of eNOS and nNOS were by Schmidt et al. (2 ) and Bredt and Snyder
Immunochemical Detection of Nitric Oxide Synthase in Human Tissue
To date three distinct isoforms of nitric oxide synthase (NOS) have been identified. Two isoforms are considered to be expressed constitutively—neu-ronal NOS (nNOS; type I NOS) and endothelial NOS (eNOS; type III NOS). The third isoform
Induced Nitric Oxide Synthase as a Major Player in the Oncogenic Transformation of Inflamed Tissue
Nitric oxide (NO) is a free radical that is involved in the inflammatory process and carcinogenesis. There are four nitric oxide synthase enzymes involved in NO production: induced nitric oxide synthase (iNOS), endothelial NO synthase (eNOS
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