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文献和实验Anti-MDR1 Ribozyme Gene Therapy
Multidrug resistance (MDR) in human cancer seriously limits the efficacy of anticancer agents. Circumvention of MDR is, thus, one of the urgent goals for successful cancer chemotherapy.
Lentiviral Vector Engineering for Anti-HIV RNAi Gene Therapy
RNA interference or RNAi-based gene therapy for the treatment of HIV-1 infection has recently emerged as a highly effective antiviral approach. The lentiviral vector system is a good candidate for the expression of antiviral short hairpin
RNAi-Inducing Lentiviral Vectors for Anti-HIV-1 Gene Therapy
RNA interference (RNAi)-based gene therapy for the treatment of HIV-1 infection provides a novel antiviral approach. For delivery of RNAi inducers to CD4+ T cells or CD34+ blood stem cells, lentiviral vectors are attractive
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