- ￥480 - 4980
- Sino Biological
- 北京
- 10014-HNAE
- 2026年01月26日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human bFGF / FGF2 Protein
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/10.00 µg/50.00 µg/100.00 µg/500.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥4980.0 |
|---|---|---|---|
| 规格： | 10.00 µg | 产品价格： | ￥480.0 |
| 规格： | 50.00 µg | 产品价格： | ￥1080.0 |
| 规格： | 100.00 µg | 产品价格： | ￥1480.0 |
| 规格： | 500.00 µg | 产品价格： | ￥4980.0 |
重组人 bFGF / FGF2 蛋白（产品说明）
蛋白名称：Human bFGF / FGF2 Protein
蛋白构建：A DNA sequence encoding the mature form of human bFGF (NP_001997.5) (Pro143-Ser288) was expressed with an additional Met at the N-terminus.
表达宿主：E. coli
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：
1.iPSC-derived human vascular organoids (Day 7) were cultured with FGF2 (Cat#10014-HNAE), VEGFA (Cat# 11066-HNAH), EGF (Cat#10605-HNAE). Red rows represent vascular organoids. Image taken at 10x magnification.(Routinely tested)
2.Measured in a cell proliferation assay using BALB/c 3T3 mouse embryonic fibroblasts.
The ED50 for this effect is typically 0.02-0.1 ng/ml.
蛋白内毒素：< 1.0 EU per μg protein as determined by the LAL method
预测N端：Met
蛋白分子量：The recombinant human bFGF consists of 147 amino acids and predicts a molecular mass of 16.5 kDa.
蛋白NP号：NP_001997.5
蛋白氨基酸序列：Pro143-Ser288
蛋白标签：Native
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称：Human bFGF / FGF2 Protein
蛋白构建：A DNA sequence encoding the mature form of human bFGF (NP_001997.5) (Pro143-Ser288) was expressed with an additional Met at the N-terminus.
表达宿主：E. coli
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：
1.iPSC-derived human vascular organoids (Day 7) were cultured with FGF2 (Cat#10014-HNAE), VEGFA (Cat# 11066-HNAH), EGF (Cat#10605-HNAE). Red rows represent vascular organoids. Image taken at 10x magnification.(Routinely tested)
2.Measured in a cell proliferation assay using BALB/c 3T3 mouse embryonic fibroblasts.
The ED50 for this effect is typically 0.02-0.1 ng/ml.
蛋白内毒素：< 1.0 EU per μg protein as determined by the LAL method
预测N端：Met
蛋白分子量：The recombinant human bFGF consists of 147 amino acids and predicts a molecular mass of 16.5 kDa.
蛋白NP号：NP_001997.5
蛋白氨基酸序列：Pro143-Ser288
蛋白标签：Native
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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- 内容
- 询问日期
文献和实验该产品被引用文献
1, Gao, Q; et al. The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis. Nature communications, PMID: 28589943
2, Shan, Y; et al. PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs. Nature communications, PMID: 28939884
3, Ou, Z; et al. A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism. Cell reports, PMID: 30865888
4, Liu, Z; et al. Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination. Neuron, PMID: 30876848
5, Zhang, F; et al. The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus. Proceedings of the National Academy of Sciences of the United States of America, PMID: 33975953
6, Zhu, Z; et al. Histone demethylase complexes KDM3A and KDM3B cooperate with OCT4/SOX2 to define a pluripotency gene regulatory network. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, PMID: 34042215
7, Wu, XL; et al. LIN28A inhibits DUSP family phosphatases and activates MAPK signaling pathway to maintain pluripotency in porcine induced pluripotent stem cells. Zoological research, PMID: 33998185
8, Chen, W; et al. Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring. Cell reports, PMID: 34731622
9, Zhang, K; et al. The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents. Nature communications, PMID: 35301318
10, Bao, F; et al. Mitolysosome exocytosis, a mitophagy-independent mitochondrial quality control in flunarizine-induced parkinsonism-like symptoms. Science advances, PMID: 35417232
11, Chen, X; et al. Integrative epigenomic and transcriptomic analysis reveals the requirement of JUNB for hematopoietic fate induction. Nature communications, PMID: 35668082 1
2, Chi, F; et al. TRG1
6, targeted by miR-76
5, inhibits breast cancer stem cell-like properties via regulating the NF-κB pathway. Molecular and cellular biochemistry, PMID: 35648115 1
3, Lv, X; et al. JUN activation modulates chromatin accessibility to drive TNFα-induced mesenchymal transition in glioblastoma. Journal of cellular and molecular medicine, PMID: 35851726 1
4, Chen, X; et al. Basic fibroblast growth factor protects against liver ischemia-reperfusion injury via the Nrf2/Hippo signaling pathway. Tissue & cell, PMID: 36150335 1
5, Mou, J; et al. HMGN5 escorts oncogenic STAT3 signaling by regulating the chromatin landscape in breast cancer tumorigenesis. Molecular cancer research : MCR, PMID: 36066963 1
6, Li, L; et al. Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination. Developmental cell, PMID: 37865085 1
7, Ye, J; et al. TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling. Cell death discovery, PMID: 37845209 1
8, Zhang, E; et al. NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling. Journal of translational medicine, PMID: 38166947 1
9, Dufresne, J; et al. Three-Dimensional Cell Culture of Epididymal Basal Cells and Organoids: A Novel Tool for Toxicology. Current protocols, PMID: 38284221
20, Xiong, G; et al. Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma. International journal of oral science, PMID: 38424060
21, Cao, L; et al. A LATS2 and ALKBH5 positive feedback loop supports their oncogenic roles. Cell reports, PMID: 38568805 2
2, Liu, X; et al. STAU1-mediated CNBP mRNA degradation by LINC00665 alters stem cell characteristics in ovarian cancer. Biology direct, PMID: 39080743 2
3, Pan, Z; et al. Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discovery. Cell stem cell, PMID: 39579761 2
4, Zhang, Y; et al. TET3-facilitated differentiation of human umbilical cord mesenchymal stem cells into oligodendrocyte precursor cells for spinal cord injury recovery. Journal of translational medicine, PMID: 39707356 2
5, Zhu, Y; et al. CPT1A-mediated MFF succinylation promotes stemness maintenance in ovarian cancer stem cells. Communications biology, PMID: 39956875 2
6, Hu, X; et al. Human induced pluripotent stem cells derived neutrophils display strong anti-microbial potencies. Cell regeneration (London, England), PMID: 40113653 2
7, Li, Z; et al. Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration. Cell reports, PMID: 40272981 2
8, Zhang, L; et al. Programmed death-ligand 1 regulates ameloblastoma growth and recurrence. International journal of oral science, PMID: 40240323 2
9, Zhang, D; et al. A cocktail hydrogel promoting the functional interneurons regeneration of human neural progenitor cells for brain injury therapy. Journal of advanced research, PMID: 40460940
30, Zhou, L; et al. Glucose restriction induces degeneration of neurons with mitochondrial DNA depletion by altering ER-mitochondria calcium transfer. Molecular psychiatry, PMID: 40461815
31, Zhu, X; et al. N6-methyladenosine on L1PA governs the trans-silencing of LTRs and restrains totipotency in naive human embryonic stem cells. Cell stem cell, PMID: 41167193
2, Shan, Y; et al. PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs. Nature communications, PMID: 28939884
3, Ou, Z; et al. A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism. Cell reports, PMID: 30865888
4, Liu, Z; et al. Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination. Neuron, PMID: 30876848
5, Zhang, F; et al. The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus. Proceedings of the National Academy of Sciences of the United States of America, PMID: 33975953
6, Zhu, Z; et al. Histone demethylase complexes KDM3A and KDM3B cooperate with OCT4/SOX2 to define a pluripotency gene regulatory network. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, PMID: 34042215
7, Wu, XL; et al. LIN28A inhibits DUSP family phosphatases and activates MAPK signaling pathway to maintain pluripotency in porcine induced pluripotent stem cells. Zoological research, PMID: 33998185
8, Chen, W; et al. Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring. Cell reports, PMID: 34731622
9, Zhang, K; et al. The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents. Nature communications, PMID: 35301318
10, Bao, F; et al. Mitolysosome exocytosis, a mitophagy-independent mitochondrial quality control in flunarizine-induced parkinsonism-like symptoms. Science advances, PMID: 35417232
11, Chen, X; et al. Integrative epigenomic and transcriptomic analysis reveals the requirement of JUNB for hematopoietic fate induction. Nature communications, PMID: 35668082 1
2, Chi, F; et al. TRG1
6, targeted by miR-76
5, inhibits breast cancer stem cell-like properties via regulating the NF-κB pathway. Molecular and cellular biochemistry, PMID: 35648115 1
3, Lv, X; et al. JUN activation modulates chromatin accessibility to drive TNFα-induced mesenchymal transition in glioblastoma. Journal of cellular and molecular medicine, PMID: 35851726 1
4, Chen, X; et al. Basic fibroblast growth factor protects against liver ischemia-reperfusion injury via the Nrf2/Hippo signaling pathway. Tissue & cell, PMID: 36150335 1
5, Mou, J; et al. HMGN5 escorts oncogenic STAT3 signaling by regulating the chromatin landscape in breast cancer tumorigenesis. Molecular cancer research : MCR, PMID: 36066963 1
6, Li, L; et al. Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination. Developmental cell, PMID: 37865085 1
7, Ye, J; et al. TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling. Cell death discovery, PMID: 37845209 1
8, Zhang, E; et al. NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling. Journal of translational medicine, PMID: 38166947 1
9, Dufresne, J; et al. Three-Dimensional Cell Culture of Epididymal Basal Cells and Organoids: A Novel Tool for Toxicology. Current protocols, PMID: 38284221
20, Xiong, G; et al. Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma. International journal of oral science, PMID: 38424060
21, Cao, L; et al. A LATS2 and ALKBH5 positive feedback loop supports their oncogenic roles. Cell reports, PMID: 38568805 2
2, Liu, X; et al. STAU1-mediated CNBP mRNA degradation by LINC00665 alters stem cell characteristics in ovarian cancer. Biology direct, PMID: 39080743 2
3, Pan, Z; et al. Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discovery. Cell stem cell, PMID: 39579761 2
4, Zhang, Y; et al. TET3-facilitated differentiation of human umbilical cord mesenchymal stem cells into oligodendrocyte precursor cells for spinal cord injury recovery. Journal of translational medicine, PMID: 39707356 2
5, Zhu, Y; et al. CPT1A-mediated MFF succinylation promotes stemness maintenance in ovarian cancer stem cells. Communications biology, PMID: 39956875 2
6, Hu, X; et al. Human induced pluripotent stem cells derived neutrophils display strong anti-microbial potencies. Cell regeneration (London, England), PMID: 40113653 2
7, Li, Z; et al. Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration. Cell reports, PMID: 40272981 2
8, Zhang, L; et al. Programmed death-ligand 1 regulates ameloblastoma growth and recurrence. International journal of oral science, PMID: 40240323 2
9, Zhang, D; et al. A cocktail hydrogel promoting the functional interneurons regeneration of human neural progenitor cells for brain injury therapy. Journal of advanced research, PMID: 40460940
30, Zhou, L; et al. Glucose restriction induces degeneration of neurons with mitochondrial DNA depletion by altering ER-mitochondria calcium transfer. Molecular psychiatry, PMID: 40461815
31, Zhu, X; et al. N6-methyladenosine on L1PA governs the trans-silencing of LTRs and restrains totipotency in naive human embryonic stem cells. Cell stem cell, PMID: 41167193
相关实验
植物源重组人胰岛素生长因子融合蛋白（OsrIGF-1），胰岛素在无血清细胞培养中的最佳替代品。 IGFs家族由两种低分子多肽(IGF-Ⅰ、IGF-Ⅱ)、两类特异性受体及六种结合蛋白组成。IGF-Ⅰ是一个有70个氨基酸的单链碱性蛋白，分子量7649Da，耐热。IGFs的生物学功能不只局限于有丝分裂刺激作用，它们也能诱导分化或促进分化功能的表达。全新推出的植物源重组人类胰岛素生长因子-1融合蛋白（OsrIGF-1）在IGF-1的N末端融合了人血清白蛋白（HSA），HSA作为蛋白质保护剂增加了IGF
脂蛋白-X 【参考范围】免疫透射比浊法：0～90mg/L. 【影响因素】标本采集及分离与测定TCH的标本抽取相同。 【临床意义】1.Lp-X是出现在阻塞性黄疸患者血清中的一种异常的低密度脂蛋白，其生成与胆汁中的卵磷脂反流有关。因而利用其这种只在胆汁淤积患者血中出现的特殊性，可以对黄疸或肝内、肝外阻塞进行一定程度的鉴别医学教|育网搜集整理。一般认为肝外胆道的梗阻比肝内的阻塞引起的胆汁淤积程度要更为严重，其参考的鉴别值为2O00mg/L. 2.在急性肝炎、肝癌、胆道
X性联无丙种球蛋白血症(X-linked agammagl，bulinemia，XLA)是临床上首次确定的体液免疫缺陷病，由Brutor于1952年报道，故又称Bruton病。XLA作为常见的原发性免疫缺陷病之一，特点为血清中各类免疫球蛋白缺乏，或只能测得微量的抗体。外周血和淋巴组织中B细胞减少或完全缺乏，淋巴结中无生发中心和浆细胞。本病起病早，在出生数月后当患儿体内的母源性抗体水平下降时开始发病。临床表现为反复化脓性感染，患者细胞免疫功能不受影响(部分患者有T细胞数量减少)，主要缺陷
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重组人 bFGF / FGF2蛋白
￥480 - 4980
