- ￥3000 - 3999
- Abbiotec
- 美国
- 252201
- 2025年07月13日
- E, WB, IHC
- Rabbit
- H
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- 详细信息
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within human IL-6R.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H
- 保质期：
1-2年
- 抗原来源：
KLH-conjugated synthetic peptide encompassing a sequence within human IL-6R.
- 目录编号：
252201
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Rabbit
- 应用范围：
E, WB, IHC
- 浓度：
见详细说明信息
- 靶点：
IL-6R
- 抗体英文名：
IL-6R Antibody
- 抗体名：
IL-6R Antibody
- 规格：
0.1 mg
IL-6R Antibody产品详细介绍：
| 产品名称： | IL-6R Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252201 |
| 规格： | 0.1 mg |
| 产品描述： | Interleukin-6R binds to IL6 with low affinity, but does not transduce a signal. A soluble IL-6R is produced by both naive and memory CD4 T cells upon TCR activation. The production of IL6-R by activated CD4 T cells is mediated by shedding of the membrane-bound IL-6R, and this process correlates with the expression of the metalloproteinase ADAM17 in these cells. In contrast to CD4 T cells, CD8 T cells do not express ADAM17 and their production of IL-6R is negligible. Thus, during an immune response CD4 T cells are an important source of IL-6R. Production of IL-6R by autoreactive CD4 T cells may contribute to their role in the development of autoimmune disease by conferring IL-6-responsiveness to cells lacking IL-6R such as synoviocytes. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within human IL-6R. |
| 适用物种： | H |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:1,000-1:10,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名： | Interleukin-6 receptor subunit alpha; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA ; IL-6R 1; Membrane glycoprotein 80; gp80; CD126 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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IL-6R Antibody_IL-6R抗体
￥3000 - 3999
