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- 2025年12月17日
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- 英文名：
TGFβ-1, human
Transforming Growth Factor β-1 (TGF-β1) is a secreted protein which belongs to the TGF-β family. TGF-β1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGF-β1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGF-β1 peptide. TGF-β1 may also form heterodimers with other TGFβ family members. It has been found that TGF-β1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
Recombinant Human TGF-β1 is produced by our mammalian cells expression system in HEK293 cells. The target protein is expressed with sequence (Leu30-Ser390) of Human TGFB1 fused with a polyhistidine tag at the C-terminus.
| 货号 | 物种 | 品名 | 规格 |
| CB055-0270 | Human | B-cell activating factor (BAFF), Human | 2.0μg |
| CB055-0280 | Bone Morphogenetic Protein-2 (BMP-2), Human | 2.0μg | |
| CB055-0300 | Ciliary Neurotrophic Factor (CNTF), Human | 2.0μg | |
| CB055-0310 | Erythropoietin (EPO), Human | 2.0μg | |
| CB055-0320 | Fibroblast Growth Factor-10 (FGF-10),Human | 2.0μg | |
| CB055-0340 | Fibroblast Growth Factor-4 (FGF-4), Human | 2.0μg | |
| CB055-0350 | Fibroblast Growth Factor-8 (FGF-8), Human | 2.0μg | |
| CB055-0061 | GM-CSF,Human | 2.0μg | |
| CB055-0531 | IFN-γ, Human | 2.0μg | |
| CB055-0641 | IL-1β, Human | 2.0μg | |
| CB055-0371 | IL-4, Human | 2.0μg | |
| CB055-0691 | Interleukin 13 (IL-13), Human | 2.0μg | |
| CB055-0651 | Interleukin-15 (IL-15), Human | 2.0μg | |
| CB055-0520 | Interleukin-2 (IL-2), Human | 2.0μg | |
| CB055-0730 | Interleukin-21 (IL-21), Human | 2.0μg | |
| CB055-0100 | Interleukin-3 (IL-3), Human | 2.0μg | |
| CB055-0390 | Interleukin-5 (IL-5), Human | 2.0μg | |
| CB055-0020 | Interleukin-6 (IL-6), Human | 2.0μg | |
| CB055-0260 | Leukemia Inhibitory Factor (LIF), human | 2.0μg | |
| CB055-0130 | M-CSF, Human | 2.0μg | |
| CB055-0160 | Noggin, Human | 2.0μg | |
| CB055-0180 | Sonic Hedgehog (C24II) (Shh), Human | 2.0μg | |
| CB055-0010 | Stem Cell Factor (SCF), human | 2.0μg | |
| CB055-0660 | TGF-α, Human | 2.0μg | |
| CB055-3240 | TGFβ-1, human | 2.0μg | |
| CB055-0450 | Tumor Necrosis Factor-alpha (TNF-α), Human | 2.0μg | |
| CB055-0230 | VEGF165 | 2.0μg | |
| CB055-1100 | Mouse | EGF, Mouse | 2.0μg |
| CB055-0030 | Flt-3L, His, Murine | 2.0μg | |
| CB055-0361 | GDNF, Mouse | 2.0μg | |
| CB055-0580 | GRO-alpha/KC/CXCL1, Mouse | 2.0μg | |
| CB055-0820 | Interleukin-10 (IL-10), Mouse | 2.0μg | |
| CB055-0120 | Interleukin-3 (IL-3), Mouse | 2.0μg | |
| CB055-0380 | Interleukin-4 (IL-4), Mouse | 2.0μg | |
| CB055-0420 | Interleukin-5 (IL-5), Mouse | 2.0μg | |
| CB055-0570 | Interleukin-6 (IL-6), His, Mouse | 2.0μg | |
| CB055-0150 | M-CSF,Mouse | 2.0μg | |
| CB055-2410 | OSM, Mouse | 2.0μg | |
| CB055-0250 | PDGF-BB, Mouse | 2.0μg | |
| CB055-0460 | Thrombopoietin (TPO), Murine | 2.0μg | |
| CB055-0590 | TNF-α (80-235aa), Mouse | 2.0μg |
依科赛细胞因子，数量有限，先到先得！
4.纯度高：HPLC检测，纯度>98%；
5.第三方认证： 美国波士顿CLIA认证机构提供质检报告；
6.GMP级别：在GMP级别厂房中生产；
1.第三方检测结果
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文献和实验Cancer Cell：整合素 αvβ6-TGFβ-SOX4 途径驱动三阴性乳腺癌的免疫逃逸
. Wucherpfennig 教授在 Cancer Cell 上在线发表了题为 Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer 的研究成果。 图片来源：Cancer Cell该研究发现，整合素 αvβ6–TGFβ–SOX4 途径驱动三阴性乳腺癌的免疫逃逸，在 TNBC 的耐药机制方面发挥着重要的作用。TNBC 细胞对细胞毒性 T 细胞的耐受性由哪些基因调控呢？研究团队采用 CRISPR/ Cas
一个发生在膜上的磷酸化引起转录因子进入核内的途径由转化生长因子TGFβ 信号引发。TGFβ 家族包括许多相关的多肽配体，能结合在有两种类型亚基的受体上。两个亚基都有丝氨酸/苏氨酸激酶活性(事实上，所有的丝氨酸/苏酸酸受体激酶都是TGFb受体家族的成员)。 配体与II型受体结合，产生与I型受体具有高亲和性的受体-配体复合物，形成一个四聚体，其中II 型受体磷酸化I 型受体。这些受体在下述情况有不同：当与TGFβ 同源的骨
人 Neuritin 酶联免疫分析(ELISA) 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本 中Neuritin 的含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中人 Neuritin 水平。用纯化的 Neuritin 抗体 包被微孔板，制成固相抗体，往包被单抗的微孔中加入 Neuritin ，再与 HRP 标记的 Neuritin 抗体结合，形成抗体
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