- ￥3000 - 3999
- Abbiotec
- 美国
- 250694
- 2025年07月12日
- E, WB, IHC
- Rabbit
- Vs
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of HIV gp120.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆抗体
- 标记物：
见下方详细说明
- 适应物种：
Vs
- 宿主：
Rabbit
- 应用范围：
E, WB, IHC
- 浓度：
见详细说明信息
- 靶点：
HIV-1 gp120
- 抗体英文名：
HIV-1 gp120 Antibody
- 抗体名：
HIV-1 gp120 Antibody
- 规格：
0.1 mg
HIV-1 gp120 Antibody产品详细介绍：
| 产品名称： | HIV-1 gp120 Antibody |
| 说明书： | http://www.abbiotec.com/antibodies/hiv-1-gp120-antibody【参考图片】 |
| 货号： | 250694 |
| 规格： | 0.1 mg |
| 产品描述： | The mature envelope protein (Env) consists of a homotrimer of noncovalently associated gp120-gp41 heterodimers. The surface protein gp120 (SU) from the human immunodeficiency virus (HIV) attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. The interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. The gp120 protein is also a ligand for CD209/DC-SIGN and CLEC4M/DC-SIGNR, which are respectively found on dendritic cells, and on endothelial cells of liver sinusoids and lymph node sinuses. These interactions allow capture of viral particles at mucosal surfaces by these cells and subsequent transmission to permissive cells. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of HIV gp120. |
| 适用物种： | Vs |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 别名： | Envelope glycoprotein gp160; Env polyprotein; Surface protein; SU; Glycoprotein 120; gp120; Human immunodeficiency virus type 1; HIV-1 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： | Speigel D et al. 2012. Yale University. 20120269766 |
ABBIOTEC产品提供质量保证，提供完善的售后和技术支持，ABBIOTEC产品正品包装：
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Inhibition of HIV Infection by Lectin Binding to gp120
Human immunodeficiency virus (HIV) is the causative agent of AIDS (acquired immunodeficiency syndrome). The polypeptide precursor gp160 of HIV-1 forms the external glycoprotein, gp120 and the transmembrane glycoprotein, gp41 (1 ). Sequence
The HIV-1 entry receptors are CD4 and a chemokine receptor (CCR5 or CXCR4). In addition it has recently been demonstrated that HIV-1 gp120 binds to and signals through integrin α4 β7 , the gut-homing receptor (Arthos et al., Nat Immunol
Characterization of HIV gp120 Envelope Glycoprotein by Lectin Analysis
The envelope glycoprotein gp120 of the human immunodeficiency virus (HIV), the causative agent of AIDS, contains approx 24 potential sites for N -glycosylation (Asn-X-Ser/Thr, X≠Pro) (1 ), all of which are utilized
技术资料暂无技术资料 索取技术资料
