Kv1.3Potassium Channel

Characterization of Potassium Channel Binding

Figure 1.17.1 Displacement of [3 H]P 1075 whole‐cell binding to KATP channels in rat A10 cells using P 1075 and two potassium channel–opener compounds. The data was fitted using GraphPad Prism program. Figure kindly contributed by R. Davis Taber

Cloning of Potassium Channel Splice Variants from Tissues and Cells

from a single gene. Due to the modular nature of proteins, alternative splicing can profoundly modify potassium channel structure, function and regulation. Alternative pre-mRNA splicing is exploited by most genes but is particularly prevalent in single gene

Photochromic Potassium Channel Blockers: Design and Electrophysiological Characterization

Voltage-gated potassium (K v ) channels are membrane proteins that open a selective pore upon membrane depolarization, allowing K+ ions to flow down their electrochemical gradient. In neurons, K v channels play a key role in repolarizing