12-O-Tiglylphorbol-13 –isobuty

Chemistry of Minor Groove Binder–Oligonucleotide Conjugates

HEPES·HCl (pH 7.2). (1) no DPI, (2) DPI1 , (3) DPI2 , (4) DPI3 . The concentration of each ODN was 2 × 10–6 M and the A/T ratio was 1:1. Curve 5 shows the melting of the DPI2 conjugate alone in the same buffer. Anomalies in the melting curves may stem

Analysis and Annotation of Whole‐Genome or Whole‐Exome Sequencing–Derived Variants for Clinical Diagnosis

Cooper, D.N., Stenson, P.D., and Chuzhanova, N.A. 2006. The Human Gene Mutation Database HGMD and its exploitation in the study of mutational mechanisms. Curr. Protoc. Bioinformatics 12:1.13.1‐1.13.20 [archived version available at http

Preparation of Oligodeoxyribonucleotides Containing the Pyrimidine(6–4)pyrimidone Photoproduct by Using a Dinucleotide Building Block

spectra of M13 vectors containing site‐specific cis‐syn, trans‐syn‐I, (6–4), and Dewar pyrimidone photoproducts of thymidylyl‐(3′→5′)‐thymidine in Escherichia coli under SOS conditions. Biochemistry 35:4146‐4154.