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- 文献和实验
- 技术资料
- 抗体名:
14-3-3ε 单克隆抗体(兔源)
- 抗体英文名:
14 3 3 epsilon Antibody, mAb, Rabbit
- 靶点:
14-3-3ε
- 浓度:
0.5mg/mL(常规浓度,以官方说明书为准)
- 应用范围:
Western Blot、免疫细胞化学 / 免疫荧光 (ICC/IF)、免疫组化 (IHC)、免疫沉淀 (IP)
- 宿主:
兔(Rabbit)
- 适应物种:
人、小鼠、大鼠
- 保质期:
- 20℃可稳定保存 半 年
- 抗原来源:
人 14-3-3ε 来源合成肽
- 级别:
科研级
- 库存:
现货
- 供应商:
上海经科化学科技有限公司
- 标记物:
无(Unconjugated)
- 克隆性:
单克隆(Monoclonal)
- 保存条件:
-20℃,可稳定保存 半 年
- 形态:
液体(Liquid)
- 亚型:
Rabbit IgG
- 免疫原:
人 14-3-3ε 来源合成肽
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1200.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥2200.0 |
| Specificity | This product is specific to 14-3-3 epsilon |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human 14-3-3 epsilon |
| Species Reactivity | Human; Mouse; Rat |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Target Background | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. |
| Synonyms | 14-3-3E; 143E; KCIP-1; MDCR; Protein kinase C inhibitor protein-1; YWHAE; |
14-3-3 epsilon 抗体、14-3-3ε 蛋白抗体、YWHAE 抗体、兔源 14-3-3 epsilon 抗体、单克隆 14-3-3 epsilon 抗体、抗 14-3-3 epsilon 抗体、细胞信号相关抗体、蛋白互作相关抗体、WB 抗体、IHC 抗体、IF 抗体、ELISA 抗体
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文献和实验antiserum specific for the C terminus of epsilon isoform, protease digestion of intact 14-3-3 showed that the N-terminal half of 14-3-3 (a 16 kDa fragment) was an intact, dimeric domain of the protein. Two isoforms of 14-3-3, tau and epsilon, were expressed
Introduction of human 14-3-3 proteins
for the C terminus of epsilon isoform,protease digestion of intact 14-3-3 showed that the N-terminal half of 14-3-3 (a 16 kDa fragment)was an intact,dimeric domain of the protein.Two isoforms of 14-3-3,tau and epsilon,were expressed in E.coli
隆抗体[14]。作用机制与MAB806相似。(4)MR1和Ua30:2MR1和Ua30:2是针对EGFRvIII缺失突变的基因融合区的ScFv。即针对合成含17氨基酸多肽(LEEKKGNYVVTDHSGGC)的单链抗体[15]。ScFv具有以下特点:良好的肿瘤组织穿透性、无交叉反应,副作用小,疗效高。四、展望由于EGFRvⅢ仅表达于肿瘤组织,它的特异性单抗就显示了良好的前景。目前基于EGFR的单克隆抗体研究较多且有的已应用于临床阶段,但大多为鼠源性,人抗鼠抗体(HAMA)产生不可避免。因此尽快制造出人鼠
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