Anti-Pertuzumab Antibody (11H4
), mAb, Mouse,Anti-Pertuzumab Antibody (11H4) 单抗 鼠源（抗帕妥珠单抗抗体 11H4）- ￥990
- 上海经科
- JK10261
- 中国
- 2026年08月22日
- ELISA、免疫印迹、免疫组化、流式细胞术
- 小鼠（Mouse）
- 通用
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- 文献和实验
- 技术资料
- 抗体名：
抗 Pertuzumab 抗体 11H4 单克隆抗体（鼠源）
- 抗体英文名：
Anti Pertuzumab Antibody 11H4 mAb Mouse
- 靶点：
Pertuzumab 抗体
- 浓度：
0.5mg/mL（常规浓度，以官方说明书为准）
- 应用范围：
ELISA、免疫印迹、免疫组化、流式细胞术
- 宿主：
小鼠（Mouse）
- 适应物种：
通用
- 保质期：
- 20℃可稳定保存 半 年
- 抗原来源：
抗 Pertuzumab 抗体 11H4 克隆
- 级别：
科研级
- 库存：
现货
- 供应商：
上海经科化学科技有限公司
- 标记物：
无（Unconjugated）
- 克隆性：
单克隆（Monoclonal）
- 保存条件：
-20℃，可稳定保存 半 年
- 形态：
液体（Liquid）
- 亚型：
Mouse IgG
- 免疫原：
抗 Pertuzumab 抗体 11H4 克隆
- 规格：
40μg
| Specificity | The product is specific for Pertuzumab (Perjeta) |
| Host Species | Mouse |
| Immunogen | Pertuzumab |
| Species Reactivity | Not applicable |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Storage Buffer | This product is lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Reconstitution | Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml. |
| Storage Instructions | The lyophilized product remains stable for 1 year at -20℃ from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8℃ or for 12 months at -20℃ or below. Avoid repeated freezing and thawing cycles. |
| Purification | Protein A chromatography |
| Isotype | IgG1,K |
| Clonality | Monoclonal |
| Clone ID | 11H4 |
| Note | We can customize this product per customer's request including product size, buffer components, etc. |
| Target Background | Pertuzumab (also called 2C4, trade name Perjeta) is a monoclonal antibody used in combination with trastuzumab and docetaxel for the treatment of metastatic HER2-positive breast cancer; it also used in the same combination as a neoadjuvant in early HER2-positive breast cancer. The epitope for pertuzumab is the domain of HER2 where it binds to HER3, and pertuzumab prevents the HER2/HER3 dimer from forming, which blocks signalling by the dimer to prevent HER2 from functioning.Anti-Pertuzumab Antibody (11H4), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Pertuzumab. |
| Synonyms | Mouse monoclonal to Pertuzumab/Perjeta |
Anti-Pertuzumab Antibody 抗体、抗帕妥珠单抗抗体、帕妥珠单抗抗体、11H4 抗体、鼠源抗体、单克隆抗体、抗药抗体、WB 抗体、IHC 抗体、IF 抗体、ELISA 抗体
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
4-Hydroxy-2-Nonenal (4-HNE) Staining by Anti-HNE Antibody
using an anti-4-HNE monoclonal antibody (MAb) (6 –8 ) and labeled goat anti-mouse IgG antibody (9 ).
相关专题单克隆抗体 单克隆抗体问世以来，在临床诊断、治疗与预防等方面发挥了巨大的作用。但是常用的鼠源单克隆抗 体具有较强的免疫原性，在临床反复应用中会引起人抗鼠抗体（ｈｕｍａｎ ａｎｔｉ －ｍｏｕｓｅ ａｎｔｉｂｏｄｙ，ＨＡＭＡ）反应， 导致半衰期缩短，治疗效果减弱。鼠源抗体人源化是指利用ＤＮＡ 重组技术和蛋白质工程技术，对抗体基 因进行重组，在保留鼠源抗体对抗原有效结合部位的同时，最大限度地降低非结合部位的鼠源性。这种通 过重组基因所表达
技术资料
