- ￥210 - 997
- TargetMol
- 美国
- T1429
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
17α-Hydroxyprogesterone
- 库存：
10
- 供应商：
TargetMol
- CAS号：
68-96-2
- 规格：
500 mg/1 mL/100 mg/50 mg
| 规格： | 500 mg | 产品价格： | ￥997.0 |
|---|---|---|---|
| 规格： | 1 mL | 产品价格： | ￥210.0 |
| 规格： | 100 mg | 产品价格： | ￥418.0 |
| 规格： | 50 mg | 产品价格： | ￥298.0 |
Product Introduction
Bioactivity
英文名:17α-Hydroxyprogesterone
描述:17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor-mediated gene expression.
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文献和实验甾类（化合物）17α-羟化酶 steroid 17α－hy- droxylase，s eroid 17α-monooxygeoase
甾类（化合物）17α-羟化酶 steroid 17α－hy- droxylase，s eroid 17α-monooxygeoase 存在于睾丸、肾上腺的微粒体部分。是一种在甾类分子的17α位置上引入羟基的酶。EC1、14、99、9。需要有分子态氧和NADPH存在，与P－450有关。例如将黄体酮和孕（甾）烯醇酮各自成为17α-羟基黄体酮和17α-羟基孕烯醇酮。在鼠的肾上腺中不存在此酶。
Quantitation of 17-OH-Progesterone (OHPG) for Diagnosis of Congenital Adrenal Hyperplasia (CAH)
Most (90%) cases of congenital adrenal hyperplasia (CAH) are due to mutations in the steroid 21-hydroxylase gene (Cyp21 ). CAH due to 21-hydroxylase deficiency is diagnosed by confirming elevations of 17-hydroxyprogesterone (OHPG
Tandem Mass Spectrometry in Hormone Measurement
chromatography-tandem mass spectrometry (LC-MS/MS) assays are replacing immunoassays for the routine measurement of testosterone, 17-hydroxyprogesterone, and other steroid hormones. Reference LC-MS/MS methods for steroid, thyroid, and peptide hormones
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