- ￥184 - 797
- TargetMol
- T1429
- 2026年07月07日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- CAS号：
68-96-2
- 规格：
1mLx10mM(inDMSO)/50mg/100mg/500mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥184.0 |
|---|---|---|---|
| 规格： | 50mg | 产品价格： | ￥254.0 |
| 规格： | 100mg | 产品价格： | ￥334.0 |
| 规格： | 500mg | 产品价格： | ￥797.0 |
Product Introduction
Bioactivity
| 名称 | 17α-Hydroxyprogesterone |
| 描述 | 17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor-mediated gene expression. |
| 体外活性 | 17α-Hydroxyprogesterone是孕酮受体（PR）的激动剂，其作用类似于孕酮[1]。它是甾体激素生物合成中的化学中间体，包括雄激素和雌激素性激素以及糖皮质激素和矿皮质激素。 |
| 体内活性 | 17-Hydroxyprogesterone是一种强效的类固醇，能够诱导GVBD（卵核破裂）[3]。 |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | 10% DMSO+90% Corn oil : 5 mg/mL (15.13 mM), Solution. 10% DMSO+90% (20% SBE-β-CD in Saline) : < 5 mg/mL (15.13 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. DMSO : 40.08 mg/mL (121.29 mM), Sonication is recommended. 10% DMSO+90% Saline : < 5 mg/mL (15.13 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. Ethanol : 61 mg/mL (184.59 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : < 5 mg/mL (15.13 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. |
| 关键字 | progestogenReceptor | progestogen Receptor | ProgesteroneReceptor | Progesterone Receptor | NR3C3 | Inhibitor | inhibit | EstrogenReceptor | Estrogen Receptor | ER | EndogenousMetabolite | Endogenous Metabolite | 17α-Hydroxyprogesterone | 17αHydroxyprogesterone | 17α Hydroxyprogesterone | 17alpha-Hydroxyprogesterone | 17a-Hydroxyprogesterone |
| 相关产品 | Formamide | Guanidine hydrochloride | Glycerol | Aceglutamide | Malic acid | DL-Lysine | Sucrose | Nicotinamide riboside malate | Gluconate Calcium | Thymidine | Corn starch | D(+)-Raffinose pentahydrate |
| 相关库 | Anti-Breast Cancer Compound Library | Bioactive Compound Library | Bioactive Compounds Library Max | Human Endogenous Metabolite Library | Gut Microbial Metabolite Library | Anti-Tumor Natural Product Library | Approved Drug Library | FDA-Approved Drug Library | Natural Product Library | Drug Repurposing Compound Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验雄烯二酮 androstenedione C19 H26 O2 ， 4-雄甾烯 -3， 17-二酮，从精巢或尿中提取出的具有雄性激素作用的一种甾类化合物。系从 17α -羟孕酮由 C17 -C20 裂解酶的作用形成的 C19 甾类化合物，以此为中间体在 17β -羟甾脱氢酶作用下生成睾酮。此化合物具有睾酮的约 1/10的雄性激素的作用。
5.99 5.82 5.69 5.60 5.52 5.46 5.37 5.27 5.17 5.06 4.96 4.85 6 7 6.54 5.89 5.52 5.28 5.12 4.99 4.90 4.82 4.76 4.67 4.57 4.47 4.36 4.25 4.14 7 8 6.06 5.42 5.05 4.82 4.65 4.53 4.43 4.36 4.29 4.20 4.10 4.00 3.89 3.78 3.67 8 9 5.71 5.08 4.72 4.48
-羟孕酮类从黄体酮衍生而得。如醋酸甲羟孕酮（醋酸甲孕酮，安宫黄体酮，medroxyprogesterone acetate）、甲地孕酮（megestrol）、氯地孕酮（chlormadinone）和羟孕酮已酸酯（17α-hydroxyprogesterone caproate）。 2.19-去甲睾丸酮类从妊娠素衍生而得。如炔诺酮（norethisterone,norethindrone, norlutin）、双醋炔诺醇（etynodiol diacetate）、炔诺孕酮（18甲基炔诺酮
技术资料暂无技术资料 索取技术资料
