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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Dasatinib monohydrate
- 库存:
10
- 供应商:
TargetMol
- CAS号:
863127-77-9
- 规格:
500 mg/10 mg/25 mg/200 mg/50 mg/100 mg/1 mL
| 规格: | 500 mg | 产品价格: | ¥2250.0 |
|---|---|---|---|
| 规格: | 10 mg | 产品价格: | ¥286.0 |
| 规格: | 25 mg | 产品价格: | ¥410.0 |
| 规格: | 200 mg | 产品价格: | ¥1330.0 |
| 规格: | 50 mg | 产品价格: | ¥671.0 |
| 规格: | 100 mg | 产品价格: | ¥893.0 |
| 规格: | 1 mL | 产品价格: | ¥279.0 |
Product Introduction
Bioactivity
英文名:Dasatinib monohydrate
描述:Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.

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文献和实验strategy to identify the spectrum of resistance-conferring mutations, which has helped in designing the next-generation BCR/ABL inhibitors such as Nilotinib, Dasatinib, and Ponatinib. Here we provide a detailed methodology for the screen
NLRP3 Inflammasome Activation and Cytotoxicity Induced by Particulate Adjuvants
particle-induced cytotoxicity. More specifically, protocols are described for the preparation and differentiation of BMDCs, their priming and stimulation using particulate NLRP3 agonists such as monosodium urate monohydrate (MSU) and the vaccine adjuvant
SILVER STAIN OF PROTEIN GELS(Ⅱ)
(monohydrate!) 0.25 ml of 36% formaldehyde
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