- 询价
- 上海沪震
- 中国/美国
- hzA050Mu01
- 2025年07月12日
- WB, ICC, IHC-P, IHC-F, ELISA
- Rabbit，兔
- 人、大鼠、小鼠、兔、、、、
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
见说明书
- 亚型：
见说明书
- 形态：
粉状
- 保存条件：
-20oC
- 克隆性：
多克隆
- 标记物：
未标记
- 适应物种：
人、大鼠、小鼠、兔、、、、
- 宿主：
Rabbit，兔
- 应用范围：
WB, ICC, IHC-P, IHC-F, ELISA
- 浓度：
200ug/ml
- 靶点：
见说明书
- 抗体英文名：
Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1)
- 抗体名：
胰岛素样生长因子1(IGF1)多克隆抗体
胰岛素样生长因子1(IGF1)多克隆抗体
Polyclonal Antibody to Insulin Like Growth Factor 1 (IGF1)
FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
| Organism species | Mus musculus (Mouse) |
| Product No. | hzA050Mu01 |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunoglobulin Type | IgG |
| Purification | Affinity Chromatography |
| Applications | WB, ICC, IHC-P, IHC-F, ELISA |
| Concentration | 200ug/ml |
| UOM | 100ug |
| Conjugate | No Conjugate |
ANTIBODY SPECIFITY
胰岛素样生长因子1(IGF1)多克隆抗体The antibody is a rabbit polyclonal antibody raised against IGF1. It has been selected for its ability to recognize IGF1 in immunohistochemical staining and western blotting.
APPLICATIONS
Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-200
Optimal working dilutions must be determined by end user.
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-200
Optimal working dilutions must be determined by end user.
CONTENTS
Form & Buffer: Supplied as solution form in PBS, pH7.4,
containing 0.02% NaN3, 50% glycerol.
containing 0.02% NaN3, 50% glycerol.
IHC Images
Used in DAB staining on fromalin fixed paraffin-embedded liver tissue
胰岛素样生长因子1(IGF1)多克隆抗体
QUALITY CONTROL
Content: The quality control contains recombinant IGF1 (Gly33~Ala102) disposed in loading buffer.
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control. Not used for other purposes.
胰岛素样生长因子1(IGF1)多克隆抗体Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol, BPB 0.01%, NaN3 0.02%.
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control. Not used for other purposes.
胰岛素样生长因子1(IGF1)多克隆抗体Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol, BPB 0.01%, NaN3 0.02%.
STORAGE
Store at 4oC for frequent use. Stored at -20oC in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.hz054Hu01 胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
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Binding Protein 4 (IGFBP4) Bos taurus; Bovine (Cattle)
hz055Cp01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Capra hircus; Caprine (Goat)
hz055Ga01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Chicken (Gallus)
hz055Hu01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Homo sapiens (Human)
hz055Mu01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Mus musculus (Mouse)
hz055Po01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Sus scrofa; Porcine (Pig)
hz056Bo01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Bos taurus; Bovine
(Cattle)
hz056Ca01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Canis familiaris;
Canine (Dog)
hz056Cp01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Capra hircus; Caprine
(Goat)
hz056Eq01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Equus caballus;
Equine (Horse)
hz056Ga01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Chicken (Gallus)
hz056Gu01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Cavia (Guinea pig )
hz056Hu01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Homo sapiens (Human)
hz056Mu01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Mus musculus (Mouse)
hz056Po01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Sus scrofa; Porcine
(Pig)
hz056Ra01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Rattus norvegicus
(Rat)
Binding Protein 3 (IGFBP3) Homo sapiens (Human)
hz054Mu01 胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 3 (IGFBP3) Mus musculus (Mouse)
hz054Po01 胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 3 (IGFBP3) Sus scrofa; Porcine (Pig)
hz054Ra01 胰岛素样生长因子结合蛋白3(IGFBP3)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 3 (IGFBP3) Rattus norvegicus (Rat)
hz055Bo01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Bos taurus; Bovine (Cattle)
hz055Cp01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Capra hircus; Caprine (Goat)
hz055Ga01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Chicken (Gallus)
hz055Hu01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Homo sapiens (Human)
hz055Mu01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Mus musculus (Mouse)
hz055Po01 胰岛素样生长因子结合蛋白4(IGFBP4)多克隆抗体 Polyclonal Antibody to Insulin Like Growth Factor
Binding Protein 4 (IGFBP4) Sus scrofa; Porcine (Pig)
hz056Bo01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Bos taurus; Bovine
(Cattle)
hz056Ca01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Canis familiaris;
Canine (Dog)
hz056Cp01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Capra hircus; Caprine
(Goat)
hz056Eq01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Equus caballus;
Equine (Horse)
hz056Ga01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Chicken (Gallus)
hz056Gu01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Cavia (Guinea pig )
hz056Hu01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Homo sapiens (Human)
hz056Mu01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Mus musculus (Mouse)
hz056Po01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Sus scrofa; Porcine
(Pig)
hz056Ra01 白介素10(IL10)多克隆抗体 Polyclonal Antibody to Interleukin 10 (IL10) Rattus norvegicus
(Rat)
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文献和实验相关实验
的物理性嗅觉干预即可显著抑制同侧嗅球中肿瘤的发生与发展。综上，利用化学遗传学以及物理方法，研究团队充分证明了嗅觉感知可以调控胶质瘤的发生。 利用硅胶塞剥夺小鼠嗅觉可以抑制嗅球中胶质瘤 接下来，研究团队对嗅觉调控胶质瘤发生的分子机制进行了探究。 通过对单侧嗅觉剥夺小鼠的两侧嗅球组织进行转录组测序，筛选出了潜在效应因子- 胰岛素样生长因子 1（IGF1）。 有趣的是，团队之前发表的工作已经证明了前癌细胞表达的 IGF1 受体（IGF1R）对胶质瘤发生发展具有重要作用，支持对 IGF1
症综合征的遗传热点。由于WAPCre系统，这种点突变只在小鼠的乳腺中活跃，通过这种突变，该菌株将在1岁左右自发地发展出与人类相关的乳腺肿瘤。我们经常让这些小鼠模型接触胰岛素样分子。频繁注射两种模型化合物AspB10和胰岛素样生长因子-1（IGF1）后，大鼠乳腺肿瘤的表达明显降低。AspB10，又称X10，是一种早期胰岛素类似物，由于增强了IGF1R结合亲和力，具有很强的启动细胞分裂的潜力。IGF1是IGF1R的天然配体，这种受体在细胞分裂信号中起着重要作用。与常规胰岛素相比，甘精胰岛素在体外实验中
的点突变而得名;一种与人类李弗罗梅尼癌症综合征基因热点相对应的基因。由于WAPCre系统，该位点突变只在小鼠乳腺中活跃，在1岁左右，该菌株会自发地发展为人类相关乳腺肿瘤。我们经常将这些小鼠模型暴露在类胰岛素分子中。频繁注射两种模型化合物AspB10和胰岛素样生长因子-1 (IGF1)后，肿瘤表达明显下降，这两种模型化合物均与大鼠乳腺肿瘤相关。AspB10，也被称为X10，是一种早期的胰岛素类似物，由于增强了IGF1R的结合亲和力，具有启动细胞分裂的强大潜力。IGF1是IGF1R的天然配体，该受体在细胞
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胰岛素样生长因子1(IGF1)多克隆抗体
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