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文献和实验Discovery of Lamin B1 and Vimentin as Circulating Biomarkers for Early Hepatocellular Carcinoma
electrophoresis (2DE) and MALDI-TOF/TOF mass spectrometry, our groups have identified lamin B1 (LMNB1) and vimentin (VIM) as promising biomarkers for detection of early HCC. Protein levels of both biomarkers were significantly elevated in cancerous tissues
相关专题 实验原理 凡能刺激机体产生抗体,并能与抗体发生特异性结合的物质称为抗原 。物质所具有的这种特性称为抗原性(Antigenicity)。当机体受抗原刺激后,在体液中出现的一种能与相应抗原发生反应的球蛋白,称免疫球蛋白(Immunoglobulin, Ig)。含有免疫球蛋白的血清称免疫血清。 医学上常见的抗原物质,种类很多,如病原微生物及其代谢产物(毒素),异种动物血清(各种抗毒素,免疫 血清
. Here, we describe the detection of autoAbs to various self-antigens with different tissue restriction patterns which includes collagens, k-α1 tubulin, vimentin, and myosin. We also discuss their relevance in monitoring for rejection following solid organ transplantation.
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