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- 文献和实验
- 技术资料
- 保存条件：
4°C, protect from light, stored under nitrogen
- 英文名：
4-Aminosalicylic acid sodium salt dihydrate
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
6018-19-5
- 规格：
10 mM * 1 mL/5 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥110.0 |
|---|---|---|---|
| 规格： | 5 g | 产品价格： | ￥100.0 |
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Sodium 4-aminosalicylate dihydrate
CAS No. : 6018-19-5
MCE 国际站：Sodium 4-aminosalicylate dihydrate
产品活性：Sodium 4-aminosalicylate (Sodium para-Aminosalicylic acid) dihydrate 是对氨基水杨酸 (PAS)，是一种二氢叶酸还原酶 (DHFR) 抑制剂和抗结核剂。PAS 通过二氢蝶酸合酶 (DHPS) 和二氢叶酸合酶 (DHFS) 纳入叶酸途径，生成羟基二氢叶酸抗代谢物，进而抑制 DHFR 酶活性。
研究领域：Anti-infection
作用靶点：Bacterial | Antibiotic
In Vitro: Sodium 4-aminosalicylate inhibits M. tuberculosis H37Rv growth with MIC value of 0.4 μM.
Sodium 4-aminosalicylate (10 μM-0.1 mM; 3 h) significantly inhibits rDHFR activity in mycobacteria. M. bovis BCG.
In Vivo: Sodium 4-aminosalicylate dihydrate
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