- ￥350 - 735
- MedChemExpress(MCE)
- 美国
- HY-B0099
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
MCI-186
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
10 mM * 1 mL/5 g/10 g/25 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥385.0 |
|---|---|---|---|
| 规格： | 5 g | 产品价格： | ￥350.0 |
| 规格： | 10 g | 产品价格： | ￥490.0 |
| 规格： | 25 g | 产品价格： | ￥735.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Edaravone
CAS No. : 89-25-8
MCE 国际站：Edaravone
产品活性：Edaravone 是一种新颖的，有效的自由基清除剂，能够抑制大鼠与 MMP-9 有关的脑出血。
研究领域：Metabolic Enzyme/Protease | Apoptosis
In Vitro: Edaravone performs both preventative and therapeutic effects against toxicity of glutamate. Pretreatment of edaravone reduces the toxicity of glutamate towards SGNs. Edaravone reduces apoptosis and necrosis caused by glutamate. Pretreatment of edaravone (500 μM) reverses these changes to approximately normal levels. The protective effect of edaravone on SGNs against glutamate-induced apoptosis is associated with PI3K/Akt pathway and Bcl-2 protein family.
In Vivo: Edaravone exerts neuroprotective effects by inhibiting endothelial injury and by ameliorating neuronal damage in brain ischemia. Edaravone provides the desirable features of NOS: it increases eNOS (beneficial NOS for rescuing ischemic stroke) and decreases nNOS and iNOS (detrimental NOS). Post-reperfusion brain edema and hemorrhagic events induced by thrombolytic therapy may be reduced by edaravone pretreatment. Edaravone significantly decreases infarct volume, with the average infarct volume in the edaravone-treated rats (227.6 mm3) being significantly lower than that in the control rats (264.0 mm3). Edaravone treatment also decreases the postischemic hemorrhage volumes (53.4 mm3 in edaravone-treated rats vs 176.4 mm3 in controls). In addition, the ratio of hemorrhage volume to infarct volume is lower in the edaravone-treated rats (23.5%) than in the untreated rats (63.2%). In edaravone (20 mg/kg)-treated rats, astrocyte activity (glial fibrillary acidic protein) and apoptotic cells (caspase-3) are decreased on the corpus callosum, germinal matrix, and cerebral cortex.
相关产品：Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | FDA-Approved Drug Library Mini | Bioactive Compound Library Plus | Apoptosis Compound Library | Metabolism/Protease Compound Library | FDA-Approved Drug Library | CNS-Penetrant Compound Library | Drug Repurposing Compound Library | Differentiation Inducing Compound Library | Anti-COVID-19 Compound Library | NMPA-Approved Drug Library | FDA Approved & Pharmacopeial Drug Library | Neuroprotective Compound Library | Drug-Induced Liver Injury (DILI) Compound Library | Anti-Pancreatic Cancer Compound Library | Angiogenesis-Related Compound Library | Food-Sourced Compound Library | Rare Diseases Drug Library | Human Metabolite Library | Anti-Pulmonary Fibrosis Compound Library | Coagulation and Anti-coagulation Compound Library | Pain-Related Compound Library | Withdrawn Drug Compound Library | Off-patent Drug Library | Membrane Protein-targeted Compound Library | Mitochondrial Toxicity Compound Library | Cell Death Library | MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | LY294002 | Tamoxifen | Paclitaxel | Y-27632 | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | SB-431542 | Actinomycin D | Deferoxamine mesylate | Bortezomib | 5-Fluorouracil | Trametinib | Sorafenib | Oxaliplatin | Gemcitabine | Temozolomide | Rotenone | Mdivi-1 | Elesclomol | Ruxolitinib | Decitabine | SP600125 | MK-2206 dihydrochloride | Etoposide | Monomethyl auristatin E
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验［摘要］ 目的：用气相色谱法测定依达拉奉合成起始原料乙酰乙酸乙酯中丙酮的残留量。方法：采用固定相为二乙烯苯乙基乙烯苯型高分子多孔小球（直径为0.18 mm～0.25 mm），氮气为载气， 用外标法测定乙酰乙酸乙酯中残留丙酮的含量。结果：该方法在丙酮浓度范围在25 μg/ml～400 μg/ml内呈良好的线性关系，响应曲线相关系数为0.996，平均回收率为96.8%。结论：本法简便，快速、实用，灵敏度高，可有效地用于乙酰乙酸乙酯的质量控制。 ［关键词］ 气相色谱法；依达拉奉乙酰
5.99 5.82 5.69 5.60 5.52 5.46 5.37 5.27 5.17 5.06 4.96 4.85 6 7 6.54 5.89 5.52 5.28 5.12 4.99 4.90 4.82 4.76 4.67 4.57 4.47 4.36 4.25 4.14 7 8 6.06 5.42 5.05 4.82 4.65 4.53 4.43 4.36 4.29 4.20 4.10 4.00 3.89 3.78 3.67 8 9 5.71 5.08 4.72 4.48
39 所中国高校入围亚洲大学百强排行榜，清华超越北大位居第二
2 月 7 日，在南方科技大学举办了的《泰晤士高等教育亚洲大学峰会》，今年的会议主题是「城市与研究型大学——共建亚洲，繁荣世界」。同时发布了 2018 年亚洲大学排名：中国共有 101 所大学入围，日本 89 所入围。这 101 所包括：内地 63 所，香港 6 所，澳门 1 所，台湾 31 所。新加坡国立大学再次蝉联榜首，清华第二，北大第三。图片来源：www.timeshighereducation.com今年是泰晤士高等教育（THE）第六次发布亚洲大学排名：共录入 25 个国家 / 地区
技术资料暂无技术资料 索取技术资料
