人类胚胎干细胞/诱导性多能干细胞/基因组编辑(hESC/iPSC/genome editing )
- Dynamic blebbing: A botileneck to human embryonic stem cell culture that can be overcome by Laminin-Integrin signaling. Weng et al., Stem Cell Research, 2018
- Integration Free Derivation of Human Induced Pluripotent Stem Cells Using Laminin 521 Matrix. Uhlin et al., J. Vis. Exp., 2017
- Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment. Rodin et al., Nature Communications, 2014
- Monolayer culturing and cloning of human pluripotent stem cells on laminin-521 based matrices under xeno-free and chemically defined conditions. Rodin et al., Nature Protocols, 2014
间充质干细胞(MSC)
- Laminin-521 Promotes Rat Bone Marrow Mesenchymal Stem Cell Sheet Formation on Light-induced Cell Sheet Technology. Jiang et al., BioMed Research International, 2016
- CD49f Acts as an Inflammation Sensor to Regulate Differentiation, Adhesion and Migration of Human Mesenchymal Stem Cells. Yang et al., Stem Cells, 2015
造血干细胞及血细胞(HSC and blood cells)
- Xeno-Free Reprogramming of Peripheral Blood Mononuclear Erythroblasts on Laminin-521. Skorik et al., Curr Protoc Stem Cell Biol. 2020
- Superior Red Blood Cell Generation from Human Pluripotent Stem Cells Through a Novel Microcarrier-Based Embryoid Body Platiorm. Sivalingam et al., Tissue eng., 2016
- Characterization of bone marrow laminins and identification of a5-containing laminins as adhesive proteins for multipotent hematopoietic FDCP-Mix cells. Gu et al., Blood, 1999
内皮细胞(Endothelial cells)
- Differentiation of Human Embryonic Stem Cells to Endothelial Progenitor Cells on Laminins in Defined and Xeno-free Systems. Nguyen et al., Stem Cell Reports, 2016
- Integrin α6β1 Is the Main Receptor for Vascular Laminins and Plays a Role in Platelet Adhesion, Activation, and Arterial Thrombosis. Schaff et al., Circulation, 2013
上皮细胞(Epithelial cells )
- Chemically defined and xenogeneic-free culture method for human epidermal keranocytes on laminin-based matrices. Tjin et al., Nature Protocols, 2020
- Biologically relevant laminin as chemically defined and fully human plaorm for human epidermal keranocyte culture. Tjin et al., Nat Communications, 2018
- Abnormal Wnt and PI3Kinase Signaling in the Malformed Intesne of lama5 Deficient Mice. Rié et al., PLOS ONE, 2012
- Polymerized Laminin-332 Matrix Supports Rapid and Tight Adhesion of Keranocytes, Suppressing Cell Migraon. Kariya et al., PLOS ONE, 2012
胰岛细胞(Pancreatic cells)
- Culturing funconal pancreac islets on α5-laminins and curave transplantaon to diabec mice. Sigmundsson et al., Matrix Biology, 2018
- Laminin 411 acts as a potent inducer of umbilical cord mesenchymal stem cell differenaon into insulin-producing cells. Qu et al., Journal of Translational Medicine, 2014
- The Vascular Basement Membrane: A Niche for Insulin Gene Expression and B Cell Proliferaon. Nikolova et al., Developmental Cell, 2006
心肌细胞(Cardiac cells)
- In Vivo Generaon of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors. Yap et al., Cell Reports, 2019
- Chemically defined generaon of human cardiomyocytes. Burridge et al., Nature methods, 2014
- A Small Molecule that Promotes Cardiac Differenaon of Human Pluripotent Stem Cells under Defined, Cytokine- and Xeno-free Condions. Minami et al., Cell Reports, 2012
肝脏细胞(Hepatic cells)
- Laminin-521 promotes quiescence in isolated stellate cells from rat liver. Rohn et al., Biomaterials, 2018
- Imaging-Based Screen Idenfies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applicaons. Ong et al., Stem Cell Reports, 2018
- Recombinant Laminins Drive the Differenaon and Self-Organizaon of hESC-Derived Hepatocytes. Cameron et al., Stem Cell Reports, 2015
- Long-Term Self-Renewal of Human ES/iPS-Derived Hepatoblast-like Cells on Human Laminin 111-Coated Dishes. Takayama et al., Stem Cell Reports, 2013
肾脏细胞(Kidney cells )
- The formation of quiescent glomerular endothelial cell monolayer in vitro is strongly dependent on the choice of extracellular matrix coating. Pajęcka et al., Experimental Cell Research, 2017
- Glomerular endothelial cells and podocytes jointly synthesize laminin-1 and -11 chains. St John et al., Kidney International, 2001
肠道细胞(Intestinal cells)
- Designer matrices for intesnal stem cell and organoid culture. Gjorevski et al., Nature letters, 2016
- Laminin α5 influences the architecture of the mouse small intesnal mucosa. Mahoney et al., J Cell Sci. 2008
肌肉细胞(Skeletal muscle cells )
- An improved method for culturing myotubes on laminins for the robust clustering of postsynaptic machinery. Pęziński et al., Scientific Reports, 2020
- Laminin 521 maintains differentiation potential of mouse and human satellite cell-derived myoblasts during long-term culture expansion . Penton et al., Skeletal Muscle, 2016
- Laminin α5 chain is required for intestinal smooth muscle development. Bolcato-Bellemin et al., Developmental Biology, 2003
神经细胞(Neural cells)
- Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures. Hyvärinen et al.,Scientific Reports, 2019
- Enhanced xeno-free differentiation of hiPSC-derived astroglia applied in a blood–brain barrier model. Delsing et al., Fluids and Barriers of the CNS, 2019
- Predictive Markers Guide Differentiation to Improve Grati Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease. Kirkeby et al., Cell Stem Cell, 2016
- The adhesion GPCR GPR126 has distinct, domain-dependent functions in Schwann cell development mediated by interaction with Laminin-211. Petersen et al., Neuron, 2015
眼细胞(Eye cells)
- Generation of Retinal Pigment Epithelial Cells Derived from Human Embryonic Stem Cells Lacking Human Leukocyte Antigen Class I and II . Petrus-Reurer et al., Stem Cell Reports, 2020
- Efficient and Scalable Directed Differentiation of Clinically Compatible Corneal Limbal Epithelial Stem Cells from Human Pluripotent Stem Cells. Hongisto et al., J. Vis. Exp., 2018
- Xeno-Free and Defined Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells Functionally Integrate in a Large-Eyed Preclinical Model. Plaza et al., Stem Cell Reports, 2015
- Laminin-511 and -521 Enable Efficient In Vitro Expansion of Human Corneal Endothelial Cells (HCEC). Okumura et al., IVOS Cornea, 2015
癌症细胞(Cancer cells)
- A laminin 511 matrix is regulated by TAZ and funcons as the ligand for the a6Bb1 integrin to sustain breast cancer stem cells. Chang et al., Research communication, 2015
- Collaboration of 3D Context and Extracellular Matrix in the Development of Glioma Stemness in a 3D Model. Ma et al., Biomaterials, 2015
动物干细胞(Animal stem cells)
- The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Boroviak et al., Nature Cell Biology, 2014
- Laminin-511 but not -332, -111, or -411 enables mouse embryonic stem cell self-renewal in vitro. Domogatskaya et al., Stem Cells, 2008
层粘连蛋白综述(Laminin Review)
- Laminins in Cellular Differentiation. Yap et al., Trends in Cell Biology, 2019
- Developing defined substrates for stem cell culture and differentiation. Hagbard et al., Phil. Trans. R. Soc. B, 2018
- Functional Diversity of Laminins. Domogatskaya et al., Annu Rev Cell Dev Biol., 2012