- ￥3290
- Abbiotec
- 美国
- 600171
- 2025年12月31日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
保存于-91℃
- 保质期：
一年
- 英文名：
Human SDF-1-alpha
- 库存：
一定量库存
- 供应商：
美国ABBIOTEC公司
- 规格：
0.01 mg
Stromal-Derived Factor (SDF-1) is a chemoattractant active on T-lymphocytes and monocytes, but not neutrophils. This cytokine activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-alpha (3-67) and SDF-1-beta (3-72) show a reduced chemotactic activity. Binding to cell surface proteoglycans inhibits formation of SDF-1-alpha (3-67), preserving the activity of SDF-1 on local sites. SDF-2 acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase SDF-1 stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. Recombinant Human SDF-1 produced in E. coli is a non-glycosylated polypeptide chain containing 68 amino acids with a MW of 8,008 Da.
形 态 ：
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
来 源 ：
E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
别 名 ：
Stromal cell-derived factor 1; SDF-1; hSDF-1; C-X-C motif chemokine 12; Pre-B cell growth stimulating factor; PBSF; Intercrine reduced in hepatomas; IRH; hIRH; SDF-1-beta(3-72); SDF-1-alpha(3-67); CXCL12; SDF1; SDF1A; SDF1B
纯 度 ：
Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
分子量 ：
8008 Da
应 用 ：E, WB
SDF-1a is fully biologically active when compared to standard. The specific activity as determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentation of 10 - 75 ng/ml.
保存条件 ：
Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
产品链接 ：http://www.abbiotec.com/proteins/human-sdf-1-alpha
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