Human CD40L,Recombinant Active

产品描述：
CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2. Recombinant Human CD40L produced in E. coli is a non-glycosylated polypeptide chain containing 149 amino acids with a MW of 16,308 Da.
形 态 ：
Each vial contains 50 ug protein lyophilized in 10 mM sodium phosphate pH7.5. Reconstitute with 0.5 ml sterile deionized water for a final concentration of 0.1 mg/ml.
来 源 ：
E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
别 名 ：
CD40 ligand; CD40-L; Tumor necrosis factor ligand superfamily member 5; TNF- related activation protein; TRAP; T-cell antigen Gp39; CD154; CD40 ligand, membrane form; CD40 ligand,soluble form; CD10LG
纯 度 ：
Purity > 98% determined by reducing and non-reducing SDS-PAGE gel and analysis by RP-HPLC. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
分子量 ：
16308 Da
应 用 ：E, WB
H-CD40L is fully biologically active when compared to standard. The ED50 as determined using T-47D cells is <0.04 ug/ml.
保存条件 ：
Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.

产品链接 ：http://www.abbiotec.com/proteins/human-cd40l