- ￥690
- CHI Scientific
- USA
- 6-1006
- 2025年12月15日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-80℃
- 保质期：
2年
- 英文名：
Pig Liver Microsomes
- 库存：
大量
- 供应商：
齐氏生物
- CAS号：
N/A
- 规格：
0.5ml、20mg/ml
肝微粒体是体外研究一个化合物的代谢(酶抑制，清除率和代谢鉴定)以及药物-药物相互作用的主要工具。通常根据特定细胞色素酶的活性水平来选择微粒体。
齐氏生物提供的肝细胞微粒体，每批产品都经过严格的制备、检测，确保批次间稳定性，然后于冻存管包装，10 mg/管；-80℃保存，干冰运输。
用途：ADME及药代动力学检测试验
种属：人/大鼠/小鼠/兔/狗/猪/猴 /牛
规格：0.5ml 20mg/ml
运输：冻存管，干冰运输。
微粒体产品被SCI论文引用（部分）：
1.Metabolism of chicoric acid by rat liver microsomes and bioactivity comparisons of chicoric acid and its metabolites
Q Liu, Y Wang, CX Xiao, W Wu, X Liu - Food & function, 2015 - pubs.rsc.org
… 11–14 Moreover, chicoric acid has showed anti-inflammatory, anti-bacterial, anti-HIV
activities, hypoglycemic and hepatocyte protective properties … Rat liver microsomes
were obtained from CHI Scientific, Inc. (Massachusetts, USA)
2.Hypoxia-triggered gene therapy: a new drug delivery system to utilize photodynamic-induced hypoxia for synergistic cancer therapy
C Huang, J Zheng, D Ma, N Liu, C Zhu, J Li… - Journal of Materials …, 2018 - pubs.rsc.org
… Rat liver microsomes were purchased from CHI Scientific (Jiangsu China … under hypoxic conditions
(red curve); DDS in the presence of inactive rat liver microsomes and NADPH … 0 represent the
fluorescence intensity of TAMRA after and before rat liver microsome addition under …
附：产品介绍
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验微粒体系列产品论文引用（参考）：
1. Metabolism of chicoric acid by rat liver microsomes and bioactivity comparisons of chicoric acid and its metabolites
Q Liu, Y Wang, CX Xiao, W Wu, X Liu - Food & function, 2015 - pubs.rsc.org
… 11–14 Moreover, chicoric acid has showed anti-inflammatory, anti-bacterial, anti-HIV
activities, hypoglycemic and hepatocyte protective properties … Rat liver microsomes
were obtained from CHI Scientific, Inc. (Massachusetts, USA) 
2. Hypoxia-triggered gene therapy: a new drug delivery system to utilize photodynamic-induced hypoxia for synergistic cancer therapy
C Huang, J Zheng, D Ma, N Liu, C Zhu, J Li… - Journal of Materials …, 2018 - pubs.rsc.org
… Rat liver microsomes were purchased from CHI Scientific (Jiangsu China … under hypoxic conditions
(red curve); DDS in the presence of inactive rat liver microsomes and NADPH … 0 represent the
fluorescence intensity of TAMRA after and before rat liver microsome addition under …
微粒体是细胞被匀浆破碎时, 内膜系统的膜结构破裂后自己重新封闭起来的小囊泡(主要是内质网和高尔基体), 这些小囊泡的直径大约100 nm左右, 是异质性的集合体, 将它们称为微粒体。 多数情况下, 微粒体是指在细胞匀浆和差速离心过程中获得的由破碎的内质网自我融合形成的近似球形的膜囊泡状结构,它包含内质网膜和核糖体两种基本成分。在体外实验中,具有蛋白质合成、蛋白质糖基化和脂类合成等内质网的基本功能。
with a transmission electron microscope. Compare the view of the compacted lysosome pellet to the structure and distribution of microsomes in an intact hepatocyte (liver cell). Use figures 7.3 and 7.4 for reference.
Metabolic Stability Assessed by Liver Microsomes and Hepatocytes
of in vitro test systems, including microsomes, cytosol or S9 fractions, hepatocytes (suspension or plated), and isolated liver slices. In drug discovery, metabolic stability is typically determined by measuring the depletion of test compound over time
