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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Catalpinoside
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
2415-24-9
- 规格：
10 mM * 1 mL/5 mg/10 mg/50 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥660.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥375.0 |
| 规格： | 10 mg | 产品价格： | ￥600.0 |
| 规格： | 50 mg | 产品价格： | ￥1500.0 |
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Catalpol
CAS No. : 2415-24-9
MCE 国际站：Catalpol
产品活性：Catalpol (Catalpinoside)，是一种在 Rehmannia glutinosa 中发现的鸢尾花苷，具有神经保护，降血糖，抗炎，抗癌，抗痉挛，抗氧化和抗 HBV 的作用。
研究领域：Anti-infection
作用靶点：HBV
In Vitro: Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length.
In Vivo: Catalpol (25-100?mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities.
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文献和实验；蒴果卵形。根状茎为传统中药，有清热生津、凉血止血、润燥、滋阴补肾、补血调经之效。含梓醇（catalpol）、地黄素（reh-mannia）、水苏糖（stachose）等多种糖及赖氨酸等多种氨基酸。 毛地黄 又称洋地黄，原产欧洲，中国有栽培。多年生直立草本，除花冠外全体被灰色柔毛和腺毛；基生叶莲座状，叶片长卵形；总状花序顶生，花朝向一边，花萼5深裂；花冠近2唇形，筒长，裂片短，紫红色，内面具斑点；雄蕊2强；蒴果卵形。叶供药用，有强心之效，现制成各种强心剂。含强心苷类。（参见彩图插页
., et al. 「Epigenetic and genetic features of 24 colon cancer cell lines.」 Oncogenesis 2.9 (2013): e71.【2】Messner, Isabelle, et al. 「KRAS p. G13D mutations are associated with sensitivity to anti-EGFR antibody treatment in colorectal cancer cell lines
) of 0.5 ml min-1, whereas unconjugated siRNAs had a t1/2 of 6 min and CL of 17.6 ml min-1. As measured by an RNase protection assay (RPA), chol-siRNAs showed broad tissue biodistribution 24 h after injection in mice. Although no detectable amounts
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