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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
121808-62-6
- 规格：
10 mM * 1 mL/100 mg/500 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥550.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥500.0 |
| 规格： | 500 mg | 产品价格： | ￥800.0 |
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Pidotimod
CAS No. : 121808-62-6
MCE 国际站：Pidotimod
产品活性：Pidotimod 是一种口服活性二肽免疫刺激剂 (immunostimulant)，具有适应性和先天免疫应答的免疫调节特性。Pidotimod 增加巨噬细胞活性和体液免疫功能。Pidotimod 可用于慢性支气管炎、慢性阻塞性肺疾病 (COPD)、支气管扩张、慢性特发性荨麻疹等的研究。
研究领域：Anti-infection
作用靶点：Bacterial
In Vivo: In toxicology study in animals, Pidotimod (oral gavage; 800 mg/kg;12 months) is non-toxic in rats and is non-toxic dogs at 600 mg/kg. Pidotimod is non-teratogenic in rats (600 mg/kg orally or 1000 mg/kg IV) and has no effects on subsequent embryofoetal development in rats (up to 1000 mg/kg/day),it has no perinatal or postnatal toxic effects in rats (600 mg/kg orally).
In ex vivo experiments in mice, Pidotimod (intraperitoneal administration; 200 mg/kg; 5 days) potentiats natural killer (NK) cell activity and produces an increase in the proliferative response to mitogens such as concanavalin A (ConA) and interleukin-2 (IL-2).
Pidotimod (intraperitoneal administration; 10-100 mg/kg) normalizes depletion of peritoneal macrophage numbers, and significantly increases macrophage superoxide anion (O2–) production in methylprednisolone-induced immunosuppressed mice.
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