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- 2025年12月05日
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- 文献和实验
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- 保存条件：
4°C, sealed storage, away from moisture
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1032008-74-4
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥933.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥360.0 |
| 规格： | 5 mg | 产品价格： | ￥848.0 |
| 规格： | 10 mg | 产品价格： | ￥1360.0 |
| 规格： | 25 mg | 产品价格： | ￥2720.0 |
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Endoxifen Z-isomer hydrochloride
CAS No. : 1032008-74-4
MCE 国际站：Endoxifen Z-isomer hydrochloride
产品活性：Endoxifen Z-isomer hydrochloride盐酸盐是最重要的Tamoxifen代谢产物, 诱导在表达ERα的乳腺癌细胞中发挥抗雌激素作用, Endoxifen抑制hERG, 这种作用具有浓度依赖性, IC50值为1.6μM。
研究领域：Vitamin D Related/Nuclear Receptor | Membrane Transporter/Ion Channel
作用靶点：Estrogen Receptor/ERR | Potassium Channel
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文献和实验Therapeutic Drug Monitoring of Tamoxifen Using LC-MS/MS
) and 4-hydroxy-N-desmethyltamoxifen (endoxifen), may be clinically useful for guiding treatment decisions. Two significant barriers to tamoxifen efficacy are: (1) variability in conversion of tamoxifen into the potent antiestrogenic metabolite, endoxifen
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