- ¥1 - 3980
- PEPROTECH
- 中国/美国
- xy-988Hu02
- 2026年01月08日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 保质期：
12个月
- 英文名：
Recombinant Toll Like Receptor 1 (TLR1)
- 库存：
1000
- 供应商：
上海信裕
| Organism species | Homo sapiens (Human) |
| Product No. | xy988Hu02 |
| Source | Prokaryotic expression |
| Host | E.coli |
| Purity | > 95% |
| UOM | 50ug |
| Predicted Molecular Mass | 27.3kDa |
| Concentration | n/a |
| Applications | SDS-PAGE; WB; ELISA; IP. |
| Endotoxin Level | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
MHHHHHHS SGLVPRGSGM KETAAAKFER QHMDSPDLGT DDDDKAMADI GSEF-DLPWYLRMVC QWTQTRRRAR NIPLEELQRN LQFHAFISYS GHDSFWVKNE LLPNLEKEGM QICLHERNFV PGKSIVENII TCIEKSYKSI FVLSPNFVQS EWCHYELYFA HHNLFHEGSN SLILILLEPI PQYSIPSSYH KLKSLMARRT YLEWPKEKSK RGLFWANLRA AINIKLTEQA K
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
Toll样受体1(TLR1)重组蛋白Ready-to-use: No need to heat, dilute or add reducing agents before use.
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文献和实验Expression Analysis of the Toll-Like Receptors in Human Peripheral Blood Mononuclear Cells
Toll-like receptors (TLRs) are key regulators of the innate and adaptive immune response to bacterial, viral, and fungal pathogens. To date, 10 human TLRs and 13 mouse TLRs have been identified and they exhibit tissue-specific mRNA/protein
对“表面Toll样受体（TLRs）”（先天免疫系统的跨膜蛋白，能够识别来自微生物的分子）的一个亚组进行刺激，被发现能够通过线粒体通道诱导可以杀菌的活性氧的生成。当“细菌”TLRs（TLR1、2和4）结合到一个配体上时，它们促使线粒体进入巨噬细胞的吞噬体，诱导“线粒体活性氧”（mROS）含量的增加。这项工作表明mROS是抗菌反应的重要成分，同时也进一步确定了线粒体在先天免疫信号作用中的核心作用。
of TLR2 can form functional pairs with TLR6 and TLR1, leading to signal transduction and cytokine gene expression. All TLRs activate signalling pathways that are similar to those activated by IL-1, because they share a Toll/IL-1R homology domain
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