Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
This gene is thought to function in extracellular matrixremodeling and migration. It is predominantly expressed in theovary, but down regulated in ovarian cancer cell lines and primarycarcinomas, suggesting its role as a tumour suppressor. Mutationsin this gene have been associated with Hennekamlymphangiectasia-lymphedema syndrome, a generalized lymphaticdysplasia in humans.
Alternate Names:
CCBE 1; ccbe1; CCBE1_HUMAN; Collagen and calcium binding EGF domain containing protein 1; Collagen and calcium binding EGF domains 1; Collagen and calcium-binding EGF domain-containing protein 1; Full of fluid protein homolog.
Specificity Reaction:Hu, Mo, Rat, Dog, Pig, Hor, Zebrafish