phospho-Crkl (Tyr207) Antibody
Cat#:PL0302314
Isotype:Rabbit Polyclonal IgG
Immunogen:PhosphoPeptide derived from human Crkl around the phosphorylation site of Tyr207 [GP(p-Y)AQ].
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Crkl is a 34kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential.
Alternate Names:
CrkL (phospho Y207); p-CrkL (phospho Y207); Crk L; Crk like protein; Crkol; HGNC:2363; Oncogene CrkL; V crk avian sarcoma virus CT10 oncogene homolog like; V crk sarcoma virus CT10 oncogene homolog avian like; CRKL_HUMAN.
Specificity Reaction:Hu, Mo, Rat, Dog, Pig, Hor,Sheep
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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