- ￥2400
- PL Laboratories
- 加拿大
- PL0402371
- 2025年07月14日
- WB: 1:100-500 IHC: 1:500-1000
- Rabbit
- Hu，Mo，Rat
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- 详细信息
- 技术资料
- 免疫原：
peptide corresponding to a sequence in the middle region of human TGF beta Receptor I.
- 亚型：
Rabbit Polyclonal IgG
- 形态：
液态
- 保存条件：
保存于-20℃
- 克隆性：
多克隆
- 标记物：
无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）
- 适应物种：
Hu，Mo，Rat
- 保质期：
按说明书条件可保存1-2年
- 抗原来源：
见详细说明资料
- 目录编号：
PL0402371
- 级别：
超纯
- 库存：
大量
- 供应商：
华拓生物
- 宿主：
Rabbit
- 应用范围：
WB: 1:100-500 IHC: 1:500-1000
- 浓度：
1mg/ml
- 靶点：
TGFBR1
- 抗体英文名：
TGFBR1 Antibody
- 抗体名：
TGFBR1抗体
- 规格：
0.1ml
TGFBR1 Antibody
Cat#：PL0402371
Isotype:Rabbit Polyclonal IgG
Immunogen：peptide corresponding to a sequence in the middle region of human TGF beta Receptor I.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
TGFBR1, Transforming growth factor, beta receptor I is a TGF beta receptor. TGFBR1 is its human gene. The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome(LDAS). TGFB1 regulates cell cycle progression by a unique signaling mechanism that involves its binding to TGFBR2 and activation of TGFBR1. Both are transmembrane serine/threonine receptor kinases. The TGFBR1 receptor may be inactivated in many of the cases of human tumor cells refractory to TGFB-mediated cell cycle arrest. Vellucci and Reiss(1997) reported that the TGFBR1 gene is approximately 31 kb long and contains 9 exons.
Alternate Names：
AAT5 antibody;Activin A receptor type II like kinase 53kDa antibody;Activin A receptor type II like kinase, 53kD antibody;Activin A receptor type II like protein kinase of 53kD antibody;activin A receptor type II-like kinase, 53kDa antibody.
Specificity Reaction：Hu，Mo，Rat
Application Notes:WB: 1:100-500 IHC: 1:500-1000
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
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TGFBR1抗体
￥2400
