peptide corresponding to a sequence at the C-terminus of human GABA Transporter 1.
亚型:
Rabbit Polyclonal IgG
形态:
液态
保存条件:
保存于-20℃
克隆性:
多克隆
标记物:
无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
适应物种:
Hu,Mo,Rat
保质期:
按说明书条件可保存1-2年
抗原来源:
见详细说明资料
目录编号:
PL0402361
级别:
超纯
库存:
大量
供应商:
华拓生物
宿主:
Rabbit
应用范围:
WB: 1:100-500 IHC: 1:500-1000
浓度:
1mg/ml
靶点:
SLC6A1
抗体英文名:
SLC6A1 Antibody
抗体名:
SLC6A1抗体
规格:
0.1ml
SLC6A1 Antibody
Cat#:PL0402361
Isotype:Rabbit Polyclonal IgG
Immunogen:peptide corresponding to a sequence at the C-terminus of human GABA Transporter 1.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
SLC6A1(Solute Carrier family 6(Neurotransmitter transporter, Gaba), Member 1), also called GABATR or GABATHG, encodes a gamma-aminobutyric acid(GABA) transporter, which removes GABA from the synaptic cleft. The SLC6A1 gene contains 15 exons and is approximately 25 kb by Lam et al. And it is mapped on 3p25.3. Zomot et al.(2007) showed that introduction of a negatively charged amino acid at or near 1 of the 2 putative sodium binding sites of the GABA transporter GAT1 from rat brain(also calledSLC6A1) renders both net flux and exchange of GABA largely chloride independent. By in vitro functional expression studies, the SLC6A1 insertion promoter(2 copies of the sequence) had significantly greater promoter activity than the noninsertion(1 copy of the sequence) promoter, which in turn had greater activity than a promoterless control.
Alternate Names:
GABATHG antibody;GABATR antibody;GABT1 antibody;GAT1 antibody;SC6A1_HUMAN antibody;SLC6A1 antibody;Sodium and chloride dependent GABA transporter 1 antibody;Sodium- and chloride-dependent GABA transporter 1 antibody.
Specificity Reaction:Hu,Mo,Rat
Application Notes:WB: 1:100-500 IHC: 1:500-1000
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.