- ￥2400
- PL Laboratories
- 加拿大
- PL0402286
- 2025年07月13日
- WB: 1:100-500 IHC: 1:500-1000
- Rabbit
- Hu
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- 详细信息
- 技术资料
- 免疫原：
peptide corresponding to a sequence at the C-terminus of human 5 Lipoxygenase.
- 亚型：
Rabbit Polyclonal IgG
- 形态：
液态
- 保存条件：
保存于-20℃
- 克隆性：
多克隆
- 标记物：
无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）
- 适应物种：
Hu
- 保质期：
按说明书条件可保存1-2年
- 抗原来源：
见详细说明资料
- 目录编号：
PL0402286
- 级别：
超纯
- 库存：
大量
- 供应商：
华拓生物
- 宿主：
Rabbit
- 应用范围：
WB: 1:100-500 IHC: 1:500-1000
- 浓度：
1mg/ml
- 靶点：
ALOX5
- 抗体英文名：
ALOX5 Antibody
- 抗体名：
ALOX5抗体
- 规格：
0.1ml
ALOX5 Antibody
Cat#：PL0402286
Isotype:Rabbit Polyclonal IgG
Immunogen：peptide corresponding to a sequence at the C-terminus of human 5 Lipoxygenase.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
ALOX5(ARACHIDONATE 5-LIPOXYGENASE), also known as LOG5 or 5-LO(5-LIPOXYGENASE), is an enzyme that in humans is encoded by the ALOX5 gene. ALOX5 is a member of the lipoxygenase family of enzymes which also transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases. The enzyme 5-lipoxygenase catalyzes 2 reactions in the formation of leukotrienes. The ALOX5 gene is mapped to chromosome 10q11.21 based on an alignment of the ALOX5 sequence with the genomic sequence. Human 5-LO contains 3 nuclear localization sequences(NLSs) and a phosphorylation site involved in nuclear localization. Compared with age-matched 5-LO competent mice, the 5-LO knockout mice developed less right heart hypertrophy. Pharmacologic inhibition or ALOX5 gene disruption resulted in a significant decrease of beta-amyloid production and gamma-secretase levels.
Alternate Names：
5 LO antibody;5-lipoxygenase antibody;5LOX antibody;5LPG antibody;Alox5 antibody;Arachidonate 5 lipoxygenase antibody;arachidonic 5-lipoxygenase alpha-10 isoform antibody;.
Specificity Reaction：Hu
Application Notes:WB: 1:100-500 IHC: 1:500-1000
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
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ALOX5抗体
￥2400
