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Granzyme A/GZMA抗体

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  • ¥2400
  • PL Laboratories
  • 加拿大
  • PL0402227
  • 2025年07月15日
  • WB: 1:100-500 IHC: 1:500-1000
  • Rabbit
  • Hu
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      peptide corresponding to a sequence in the middle region of human Granzyme A.

    • 亚型

      Rabbit Polyclonal IgG

    • 形态

      液态

    • 保存条件

      保存于-20℃

    • 克隆性

      多克隆

    • 标记物

      无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)

    • 适应物种

      Hu

    • 保质期

      按说明书条件可保存1-2年

    • 抗原来源

      见详细说明资料

    • 目录编号

      PL0402227

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      华拓生物

    • 宿主

      Rabbit

    • 应用范围

      WB: 1:100-500 IHC: 1:500-1000

    • 浓度

      1mg/ml

    • 靶点

      Granzyme A/GZMA

    • 抗体英文名

      Granzyme A/GZMA Antibody

    • 抗体名

      Granzyme A/GZMA抗体

    • 规格

      0.1ml

    产品细节图片1
    Granzyme A/GZMA Antibody
    Cat#:PL0402227
    Isotype:Rabbit Polyclonal IgG
    Immunogen:peptide corresponding to a sequence in the middle region of human Granzyme A.
    Purification: Immunogen affinity purified

    Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

    Background:
    Granzyme A is a protein that in humans is encoded by the GZMA gene. Cytolytic T lymphocytes(CTL) and natural killer(NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are though to protect their host by lysing cells bearing on their surface "nonself" antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
    Alternate Names:
    CTL tryptase antibody;CTLA3 antibody;Cytolytic t cell and natural killer cell specific trypsin like serine protease antibody;Cytotoxic T lymphocyte associated serine esterase 3 antibody;Cytotoxic T lymphocyte proteinase 1 antibody;Fragmentin 1 antibody;GRAA_HUMAN antibody.
    Specificity Reaction:Hu
    Application Notes:WB: 1:100-500 IHC: 1:500-1000
    Storage :
    Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

    This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
    PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。

    产品细节图片2 产品细节图片3 产品细节图片4
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    图标文献和实验
    相关实验
    • Granzyme A、B介导的凋亡信号通路

      相关专题   T细胞被激活后,释放含穿孔素与颗粒酶的颗粒,在Ca2+的借助下,颗粒在靶细胞膜 上穿孔,进而颗粒酶(granzyme)进入靶细胞内,引起靶细胞DNA降解活动。对这种颗粒酶的研究也较多,已从人及鼠体内提取了10余种酶,认为起主要作用的是granzymea与granzymeB。 One mechanism used by cytotoxic T cells to kill tumor cells

    • Immunodetection of Granzyme B Tissue Distribution and Cellular Localisation

      Investigation of Granzyme B (GrB) function and pathophysiology in both human settings and rodent models increasingly involve the use of indirect immunofluorescence imaging and fluorescence-activated cell sorting, which requires reliable GrB

    • Detection of Human and Mouse Granzyme B Activity in Cell Extracts

      The serine protease granzyme B (GrB) is a key effector molecule in cell-mediated immunity, released by cytotoxic lymphocytes (CLs) to induce cell death in neoplastic or virus-infected cells. The ability to detect and measure GrB activity

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