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- 详细信息
- 技术资料
- 免疫原:
peptide corresponding to a sequence at the C-terminus of human Muscarinic Acetylcholine Receptor 2.
- 亚型:
Rabbit Polyclonal IgG
- 形态:
液态
- 保存条件:
保存于-20℃
- 克隆性:
多克隆
- 标记物:
无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
- 适应物种:
Hu,Mo,Rat
- 保质期:
按说明书条件可保存1-2年
- 抗原来源:
见详细说明资料
- 目录编号:
PL0401180
- 级别:
超纯
- 库存:
大量
- 供应商:
华拓生物
- 宿主:
Rabbit
- 应用范围:
WB: 1:100-500 IHC: 1:500-1000
- 浓度:
1mg/ml
- 靶点:
CHRM2
- 抗体英文名:
CHRM2 Antibody
- 抗体名:
CHRM2抗体
- 规格:
0.1ml
CHRM2 Antibody
Cat#:PL0401180
Isotype:Rabbit Polyclonal IgG
Immunogen:peptide corresponding to a sequence at the C-terminus of human Muscarinic Acetylcholine Receptor 2.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor. The M2 muscarinic receptors are located in the heart, where they act to slow the heart rate down to normal sinus rhythm after stimulatory actions of the sympathetic nervous system, by slowing the speed of depolarization. The CHRM2 gene inhibits the release of acetylcholine from cholinergic fibers in the lungs and elsewhere. In airway parasympathetic neurons, it is decreased by viral infections and by interferon-gamma, increasing actylcholine release. This gene is though to be involved in neuronal excitability, synaptic plasticity and feedback regulation of acetylcholine release and has previously been implicated in higher cognitive processing. In a sample of 667 individuals from 304 families, Gosso MF et al. genotyped three single-nucleotide polymorphisms(SNPs) in the CHRM2 gene on 7q31-35. CHRM2 is implicated in memory and cognition, functions impaired in many neuropsychiatric disorders.
Alternate Names:
7TM receptor antibody;Acetylcholine receptor, muscarinic, 2 antibody;Acm2 antibody;ACM2_HUMAN antibody;Cholinergic receptor muscarinic 2 antibody;Cholinergic receptor, muscarinic 2, cardiac antibody;Cholinergic receptor, muscarinic 2, isoform a antibody;Cholinergic receptor, muscarinic 2a antibody;CHRM2 antibody;chrm2a antibody;CM2 antibody;HM2 antibody;M2 antibody;M2 muscarinic receptor antibody;Muscarinic acetylcholine receptor M2 antibody;Muscarinic M2 receptor antibody.
Specificity Reaction:Hu,Mo,Rat
Application Notes:WB: 1:100-500 IHC: 1:500-1000
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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CHRM2抗体
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