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HSP70s抗体

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  • ¥2400
  • PL Laboratories
  • 加拿大
  • PL0401122
  • 2025年07月10日
  • WB: 1:100-500 IHC: 500-1000 ICC: 1:500-1000
  • Rabbit
  • Hu, Mo, Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      peptide corresponding to a sequence at the N-terminus of human Hsc70.

    • 亚型

      Rabbit Polyclonal IgG

    • 形态

      液态

    • 保存条件

      保存于-20℃

    • 克隆性

      多克隆

    • 标记物

      无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)

    • 适应物种

      Hu, Mo, Rat

    • 保质期

      按说明书条件可保存1-2年

    • 抗原来源

      见详细说明资料

    • 目录编号

      PL0401122

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      华拓生物

    • 宿主

      Rabbit

    • 应用范围

      WB: 1:100-500 IHC: 500-1000 ICC: 1:500-1000

    • 浓度

      1mg/ml

    • 靶点

      HSP70s

    • 抗体英文名

      HSP70s Antibody

    • 抗体名

      HSP70s抗体

    • 规格

      0.1ml

    产品细节图片1
    HSP70s Antibody
    Cat#:PL0401122
    Isotype:Rabbit Polyclonal IgG
    Immunogen:peptide corresponding to a sequence at the N-terminus of human Hsc70.
    Purification: Immunogen affinity purified

    Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

    Background:
    The 70 kilodalton heat shock proteins(Hsp70s) are a family of ubiquitously expressed heat shock proteins. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress. All of the Hsp70 proteins have three major functional domains: An N-terminal ATPase domain binds ATP(Adenosine triphosphate) and hydrolyzes it to ADP(Adenosine diphosphate); A substrate binding domain contains a groove with an affinity for neutral, hydrophobic amino acid residues; A C-terminal domain rich in alpha helical structure acts as a 'lid' for the substrate binding domain. By binding tightly to partially-synthesized peptide sequences(incomplete proteins), Hsp70 prevents them from aggregating and being rendered nonfunctional. And it also can act to protect cells from thermal or oxidative stress. Finally, Hsp70 seems to be able to participate in disposal of damaged or defective proteins.
    Alternate Names:
    Constitutive heat shock protein 70 antibody;Heat shock 70kD protein 10 antibody;Heat shock 70kD protein 8 antibody;Heat shock 70kDa protein 8 antibody;Heat shock cognate 71 kDa protein antibody;Heat shock cognate 71 kDa protein. antibody;Heat shock cognate protein 54 antibody;Heat shock cognate protein 71 kDa antibody;Heat shock protein 8 antibody;Heat shock protein A8 antibody;Heat-shock70-KD protein 10, formerly antibody;HSC54 antibody;HSC71 antibody;Hsc73 antibody;HSP7C_HUMAN antibody;HSPA10 antibody;HSPA8 antibody;LAP1 antibody;Lipopolysaccharide associated protein 1 antibody;LPS associated protein 1 antibody;LPS associated protein antibody;N-myristoyltransferase inhibitor protein 71 antibody;NIP71 antibody.
    Specificity Reaction:Hu, Mo, Rat
    Application Notes:WB: 1:100-500 IHC: 500-1000 ICC: 1:500-1000
    Storage :
    Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

    This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
    PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。

    产品细节图片2 产品细节图片3 产品细节图片4
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    图标文献和实验
    相关实验
    • Nucleotide Exchange Factors for Hsp70 Chaperones

      The ATPase cycle of Hsp70 chaperones controls their transient association with substrate and, thus, governs their function in protein folding. Nucleotide exchange factors (NEFs) accelerate ADP release from Hsp70 which results in rebinding

    • Hsp70: Anti-apoptotic and Tumorigenic Protein

      Heat shock protein 70 (Hsp70) is a powerful chaperone whose expression is induced in response to a wide variety of physiological and environmental insults, including anticancer chemotherapy, thus allowing the cell to survive to lethal

    • Quantification of HSP27 and HSP70 Molecular Chaperone Activities

      Stress-inducible heat-shock proteins (HSPs, like HSP70 and HSP27) are molecular chaperones that �protect cells from stress damage by keeping cellular proteins in a folding competent state and preventing them from irreversible aggregation. HSP

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