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- 技术资料
- 免疫原:
peptide corresponding to a sequence at the C-terminus of human P2X3.
- 亚型:
Rabbit Polyclonal IgG
- 形态:
液态
- 保存条件:
保存于-20℃
- 克隆性:
多克隆
- 标记物:
无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
- 适应物种:
Hu, Mo, Rat
- 保质期:
按说明书条件可保存1-2年
- 抗原来源:
见详细说明资料
- 目录编号:
PL0401121
- 级别:
超纯
- 库存:
大量
- 供应商:
华拓生物
- 宿主:
Rabbit
- 应用范围:
WB: 1:100-500 IHC: 500-1000
- 浓度:
1mg/ml
- 靶点:
P2X3
- 抗体英文名:
P2X3 Antibody
- 抗体名:
P2X3抗体
- 规格:
0.1ml
P2X3 Antibody
Cat#:PL0401121
Isotype:Rabbit Polyclonal IgG
Immunogen:peptide corresponding to a sequence at the C-terminus of human P2X3.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Purinergic receptor P2X, ligand-gated ion channel, 3, also known as P2X3, is a human gene. Its gene is mapped to 11q12. P2X purinoceptors are 397 to 492 amino acids long and have a predicted structure of 2 short intracellular domains, 2 transmembrane-spanning regions, and a large extracellular domain. The P2X3 subunit has 43% and 47% identity with P2X1 and P2X2, respectively; 10 cysteine residues are conserved in all 3 subtypes, so that tertiary structures may also be conserved. P2X3 was the only ligand-gated channel known to be expressed exclusively by a subset of sensory neurons. The remarkable selectivity of expression of the channel, coupled with a sensory neuron-like pharmacology, suggested that it may transduce ATP-evoked nociceptor activation. If ATP, and more specifically, P2X3 purinoceptors are involved in nociception, then the development of an antagonist selective for P2X3 could prove useful in pain relief.
Alternate Names:
ATP receptor antibody;P2RX3 antibody;P2RX3_HUMAN antibody;P2X purinoceptor 3 antibody;P2X receptor subunit 3 antibody;P2X3 antibody;Purinergic receptor antibody;Purinergic receptor P2X ligand gated ion channel 3 antibody;Purinergic receptor P2X3 antibody;Purinoceptor P2X3 antibody.
Specificity Reaction:Hu, Mo, Rat
Application Notes:WB: 1:100-500 IHC: 500-1000
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。
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P2X3抗体
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