peptide corresponding to a sequence at the N-terminus of human Estrogen Receptor beta.
亚型:
Rabbit Polyclonal IgG
形态:
液态
保存条件:
保存于-20℃
克隆性:
多克隆
标记物:
无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
适应物种:
Hu
保质期:
按说明书条件可保存1-2年
抗原来源:
见详细说明资料
目录编号:
PL0401103
级别:
超纯
库存:
大量
供应商:
华拓生物
宿主:
Rabbit
应用范围:
WB: 1:100-500
浓度:
1mg/ml
靶点:
Erβ
抗体英文名:
Erβ Antibody
抗体名:
Erβ抗体
规格:
0.1ml
Erβ Antibody
Cat#:PL0401103
Isotype:Rabbit Polyclonal IgG
Immunogen:peptide corresponding to a sequence at the N-terminus of human Estrogen Receptor beta.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Estrogen receptor-beta, referred to as ESR2, is a member of the superfamily of nuclear receptors, which can transduce extracellular signals into transcriptional responses. This gene is mapped to 14q and comprises 8 exons spanning approximately 40 kb. ESR2 is expressed in multiple tissues, including developing spermatids of the testis and in ovarian granulosa cells. ESR-beta is homologous to the previously identified ESR-alpha and has an overlapping but nonidentical tissue distribution. The DNA-binding domain of ESR-beta is 96% conserved compared to ESR, and the ligand-binding domain shows 58% conserved residues. ESR-beta is expressed in human thymus, spleen, ovary, and testis. Rat ESR-beta is expressed in rat prostate and ovary and is homologous to rat ESR(95% conserved DNA-binding domain; 55% conserved ligand-binding domain). ESR2 mRNA was coexpressed with ESR1 and its splice variants in 60% of prolactinomas, 100% of mixed growth hormone /prolactin tumors, and 29% of gonadotroph tumors.
Alternate Names:
ER BETA antibody;Erb antibody;ESR BETA antibody;ESR2 antibody;ESR2_HUMAN antibody;ESRB antibody;ESTRB antibody;estrogen nuclear receptor beta variant a antibody;estrogen nuclear receptor beta variant b antibody;estrogen receptor 2(ER beta) antibody;Estrogen Receptor 2 antibody;estrogen receptor beta 4 antibody;Estrogen receptor beta antibody;NR3A2 antibody;Nuclear receptor subfamily 3 group A member 2 antibody.
Specificity Reaction:Hu
Application Notes:WB: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.