- ￥3000 - 3999
- Abbiotec
- 美国
- 254527
- 2025年07月16日
- E, WB, IHC
- Rabbit
- H, M, R
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- 详细信息
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human cyclin D3.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A and antigen affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H, M, R
- 宿主：
Rabbit
- 应用范围：
E, WB, IHC
- 浓度：
见详细说明信息
- 靶点：
Cyclin D3
- 抗体英文名：
Cyclin D3 Antibody
- 抗体名：
Cyclin D3 Antibody
- 规格：
0.1 mg
Cyclin D3 Antibody产品详细介绍：
| 产品名称： | Cyclin D3 Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 254527 |
| 规格： | 0.1 mg |
| 产品描述： | Cyclin D3 (CCND3) is a regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Cyclin D3 hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenic and antimitogenic signals. Cyclin D3 is also a substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, it is required for nuclear translocation and activity of the cyclin D-CDK4 complex. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human cyclin D3. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名： | Cyclin D3; G1/S-specific cyclin-D3; CCND3 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A and antigen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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Cyclin D3 Antibody
￥3000 - 3999
