- ¥1 - 3980
- PEPROTECH
- 中国/美国
- xy-494Ra01
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 保质期：
12个月
- 英文名：
Recombinant Janus Kinase 2 (JAK2)
- 库存：
1000
- 供应商：
上海信裕
| Organism species | Rattus norvegicus (Rat) |
| Product No. | xy494Ra01 |
| Source | Prokaryotic expression |
| Host | E.coli |
| Purity | > 95% |
| UOM | 50ug |
| Predicted Molecular Mass | 15.0kDa |
| Concentration | n/a |
| Applications | SDS-PAGE; WB; ELISA; IP. |
| Endotoxin Level | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
MGHHHHHHSGSEF-TG NPPFIKP GISITVLPKD ILQERIPWVP PECIENPKNL TLATDKWSFG TTLWEICSGG DKPLSALDSQ RKLQFYEDKH QLPAPKWTEL ANLINTCMDY EPDFRPAFRA VIRDLNS
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
Janus激酶2(JAK2)重组蛋白Ready-to-use: No need to heat, dilute or add reducing agents before use.
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文献和实验受体相关性蛋白酪氨酸激酶介导的信号途径 大部分细胞因子受体分子胞内区不带有启动信号转导的蛋白酪氨酸激酶(PTK)结构域，但可通过相应胞内区连接的PTK起作用。CkR―F和IFNR―F的受体分子胞内区都结合有PTK中的Janus激酶(Janus kinase，Jak)家族成员，包括Jakl、Jak2、Jak3和Tyk2。细胞因子各种受体的亚单位往往连接Jak家族中的一个或几个特定成员。如C―CSFR与Jak2连接，IL2Rβ链与Jakl、IL2Rγ链与Jak3连接，ILl0R
0495 EGFR图示 coven 胞外区没有激酶活性，只是胞外区的结构会调节EGFR的激酶活性。对于药物筛选来说，你要选择的是酪氨酸激酶，我们现在用的是Invitrogen的产品，货号是SKU# PV3872，你可以查查。 你在选产品的时候一定要选激酶，不要选重组蛋白，因为重组蛋白不一点都是激酶，有的是用来做标准品或ELISA等其他用途的。对于激酶, CST和Invitrogen都有卖,别的公司也有,这个我就不太清楚了,不过个人
Immunoprecipitation to Determine JAK Kinase Activation in Response to Interleukins in Ovarian Cancer
In cytokine receptors, there is no consensus sequence motif for tyrosine and/or serine/threonine kinases in its intracellular domain (1 ). Cytokine receptors associate with and activate members of the Janus kinase family (JAK
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