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112203300
HM
human
否
神经组织
原代细胞
否
原代细胞
否
否
咨询销售
贴壁生长
5-10年
干冰
Human
不是
大量
中乔新舟
5 x 10^5 cells/vial
人小神经胶质细胞(Human Microglia)说明:
货号:1900
人小胶质细胞提取自人大脑细胞,原代冻存,每管细胞数量>50万粒.
Description
Microglia, one of the glial cell types in the CNS, is an important integral component of neuro-glial
cell network [1]. They have been observed in the brain parenchyma from the early stage of development
to the mature state. Microglia act as brain macrophages when programmed cell death occurs during
brain development or when the CNS is injured or pathologically damaged. Microglia can be considered
as the main cell in brain immune surveillance, can present antigens in the molecular context of MHC
class II expression to CD-4 positive T cells, are capable of Fc-mediated phagocytosis, and share many
common antigens with hemopoietic and tissue macrophages [2]. Furthermore, there is accumulating
evidence that microglia are involved in a variety of physiological and pathological processes in the
brain by interacting with neurons and other glial cells and through production of biologically active
substances such as growth factors, cytokines, and other factors [3].
HM from ScienCell Research Laboratories are isolated from primary human brain cell culture. HM is
characterized by immunofluorescent method with antibody to OX-42 (CD 11b/c). HM is negative for HIV-1,
HBV, HCV, mycoplasma, bacteria, yeast and fungi. HM is guaranteed to further culture in the condition
provided by ScienCell Research Laboratories.
Recommended Medium
It is recommended to use Microglia Medium (MM, Cat. No. 1901) for the culturing of HM in vitro.
Product Use
HM are for research use only. They are not approved for human or animal use, or for application in in vitro
diagnostic procedures.
Shipping
Dry ice or gel ice.
Reference
[1] Lee, S. C., Liu, W., Brosnan, C. F. and Dickson, D. W. (1992) Characterization of primary human fetal
dissociated central nervous system cultures with an emphasis on microgia. Laboratory Investigation.
67:465-476.
[2] Fedoroff, S., Zhai, R. and Novak, J. P. (1997) Microglia and astroglia have a common progenitor cell. J.
Neurosci. Res. 50: 477-486.
[3] Stoll, G. and Jander, S. (1999) The role of microglia and macrophages in the pathophysiology of the CNS.
Prog. Neurobiol. 58:233-247.
Sciencell产品目录:
神经系统 | |||
中文名 | 货号 | 简称 | 英文名称 |
人脑微血管内皮细胞 | 1000 | HBMEC | Human Brain Microvascular Endothelial Cells |
人脑血管平滑肌细胞 | 1100 | HBVSMC | Human Brain Vascular Smooth Muscle Cells |
人脑血管外膜成纤维细胞 | 1110 | HBVAF | Human Brain Vascular Adventitial Fibroblasts |
人脑血管周细胞 | 1200 | HBVP | Human Brain Vascular Pericytes |
人脉络丛内皮细胞 | 1300 | HCPEC | Human Choroid Plexus Endothelial Cells |
人脉络丛上皮细胞 | 1310 | HCPEpiC | Human Choroid Plexus Epithelial Cells |
人脉络丛成纤维细胞 | 1320 | HCPF | Human Choroid Plexus Fibroblasts |
人脑膜细胞 | 1400 | HMC | Human Meningeal Cells |
人神经元 | 1520 | HN | Human Neurons |
人小脑颗粒细胞 | 1530 | HCGC | Human Cerebellar Granule Cells |
人神经元-海马 | 1540 | HN-h | Human Neurons-hippocampal |
人神经元-中脑 | 1550 | HN-mb | Human Neurons-midbrain |
人神经元-脑干 | 1560 | HN-bs | Human Neurons-brain stem |
人少突胶质前体细胞 | 1600 | HOPC | Human Oligodendrocyte Precursor Cells |
人少突胶质前体细胞-球状 | 1610 | HOPC-os | Human Oligodendrocyte Precursor Cell-oligospheres |
人雪旺细胞 | 1700 | HSC | Human Schwann Cells |
人神经束膜细胞 | 1710 | HPNC | Human Perineurial Cells |
人星形胶质细胞 | 1800 | HA | Human Astrocytes |
人星形胶质细胞-小脑 | 1810 | HA-c | Human Astrocytes-cerebellar |
人星形胶质细胞-脊髓 | 1820 | HA-sp | Human Astrocytes-spinal cord |
人星形胶质细胞- 海马 | 1830 | HA-h | Human Astrocytes-hippocampal |
人星形胶质细胞- 脑干 | 1840 | HA-bs | Human Astrocytes-brain stem |
人星形胶质细胞- 中脑 | 1850 | HA-mb | Human Astrocytes-midbrain |
人视网膜星形胶质细胞 | 1870 | HRA | Human Retinal Astrocytes |
人小神经胶质细胞 | 1900 | HM | Human Microglia |
大鼠细胞系统 | |||
中文名 | 货号 | 简称 | 英文名称 |
大鼠脑微血管内皮细胞 | R1000 | RBMEC | Rat Brain Microvascular Endothelial Cells |
大鼠垂体细胞 | R1200 | RPC | Rat Pituitary Cells |
大鼠脑膜细胞 | R1400 | RMC | Rat Meningeal Cells |
大鼠脑脊神经元 | R1510 | RN-r | Rat Neurons-raphe |
大鼠皮质神经元 | R1520 | RN-c | Rat Neurons-cortical |
大鼠颗粒细胞 | R1530 | RGC | Rat Granule Cells |
大鼠神经元- 海马 | R1540 | RN-h | Rat Neurons-hippocampal |
大鼠黑质神经元 | R1550 | RN-sn | Rat Neurons-substantia nigra |
大鼠纹状体神经元 | R1560 | RN-s | Rat Neurons-striatal |
大鼠腹脊髓神经元 | R1570 | RN-vsc | Rat Neurons-ventral spinal cord |
大鼠背脊髓神经元 | R1580 | RN-dsc | Rat Neurons-dorsal spinal cord |
大鼠背脊髓神经元 | R1590 | RN-sc | Rat Neurons-spinal cord |
大鼠少突胶质前体细胞 | R1600 | ROPC | Rat Oligodendrocyte Precursor Cells |
大鼠雪旺细胞 | R1700 | RSC | Rat Schwann Cells |
大鼠神经束膜成纤维细胞 | R1710 | RPNF | Rat Perineurial Fibroblasts |
大鼠星形胶质细胞 | R1800 | RA | Rat Astrocytes |
大鼠星形胶质细胞- 小脑 | R1810 | RA-c | Rat Astrocytes-cerebellar |
大鼠星形胶质细胞- 海马 | R1820 | RA-h | Rat Astrocytes-hippocampal |
大鼠小神经胶质细胞 | R1900 | RM | Rat Microglia |
大鼠巨噬细胞 | R1920 | RMa | Rat Macrophage |
近几年的新药研发成功率在逐年下降,其根本原因之一就是传统的药物筛选系统是建立在只具有30-40%
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