人小神经胶质细胞

人小神经胶质细胞(Human Microglia)说明：

货号：1900



人小胶质细胞提取自人大脑细胞,原代冻存,每管细胞数量>50万粒.

Description

Microglia, one of the glial cell types in the CNS, is an important integral component of neuro-glial
cell network [1]. They have been observed in the brain parenchyma from the early stage of development
to the mature state. Microglia act as brain macrophages when programmed cell death occurs during
brain development or when the CNS is injured or pathologically damaged. Microglia can be considered
as the main cell in brain immune surveillance, can present antigens in the molecular context of MHC
class II expression to CD-4 positive T cells, are capable of Fc-mediated phagocytosis, and share many
common antigens with hemopoietic and tissue macrophages [2]. Furthermore, there is accumulating
evidence that microglia are involved in a variety of physiological and pathological processes in the
brain by interacting with neurons and other glial cells and through production of biologically active
substances such as growth factors, cytokines, and other factors [3].

HM from ScienCell Research Laboratories are isolated from primary human brain cell culture. HM is
characterized by immunofluorescent method with antibody to OX-42 (CD 11b/c). HM is negative for HIV-1,
HBV, HCV, mycoplasma, bacteria, yeast and fungi. HM is guaranteed to further culture in the condition
provided by ScienCell Research Laboratories.

Recommended Medium

It is recommended to use Microglia Medium (MM, Cat. No. 1901) for the culturing of HM in vitro.

Product Use

HM are for research use only. They are not approved for human or animal use, or for application in in vitro
diagnostic procedures.

Shipping

Dry ice or gel ice.

Reference

[1] Lee, S. C., Liu, W., Brosnan, C. F. and Dickson, D. W. (1992) Characterization of primary human fetal
dissociated central nervous system cultures with an emphasis on microgia. Laboratory Investigation.
67:465-476.
[2] Fedoroff, S., Zhai, R. and Novak, J. P. (1997) Microglia and astroglia have a common progenitor cell. J.
Neurosci. Res. 50: 477-486.
[3] Stoll, G. and Jander, S. (1999) The role of microglia and macrophages in the pathophysiology of the CNS.
Prog. Neurobiol. 58:233-247.
Sciencell产品目录:

神经系统
中文名	货号	简称	英文名称
人脑微血管内皮细胞	1000	HBMEC	Human Brain Microvascular Endothelial Cells
人脑血管平滑肌细胞	1100	HBVSMC	Human Brain Vascular Smooth Muscle Cells
人脑血管外膜成纤维细胞	1110	HBVAF	Human Brain Vascular Adventitial Fibroblasts
人脑血管周细胞	1200	HBVP	Human Brain Vascular Pericytes
人脉络丛内皮细胞	1300	HCPEC	Human Choroid Plexus Endothelial Cells
人脉络丛上皮细胞	1310	HCPEpiC	Human Choroid Plexus Epithelial Cells
人脉络丛成纤维细胞	1320	HCPF	Human Choroid Plexus Fibroblasts
人脑膜细胞	1400	HMC	Human Meningeal Cells
人神经元	1520	HN	Human Neurons
人小脑颗粒细胞	1530	HCGC	Human Cerebellar Granule Cells
人神经元-海马	1540	HN-h	Human Neurons-hippocampal
人神经元-中脑	1550	HN-mb	Human Neurons-midbrain
人神经元-脑干	1560	HN-bs	Human Neurons-brain stem
人少突胶质前体细胞	1600	HOPC	Human Oligodendrocyte Precursor Cells
人少突胶质前体细胞-球状	1610	HOPC-os	Human Oligodendrocyte Precursor Cell-oligospheres
人雪旺细胞	1700	HSC	Human Schwann Cells
人神经束膜细胞	1710	HPNC	Human Perineurial Cells
人星形胶质细胞	1800	HA	Human Astrocytes
人星形胶质细胞-小脑	1810	HA-c	Human Astrocytes-cerebellar
人星形胶质细胞-脊髓	1820	HA-sp	Human Astrocytes-spinal cord
人星形胶质细胞- 海马	1830	HA-h	Human Astrocytes-hippocampal
人星形胶质细胞- 脑干	1840	HA-bs	Human Astrocytes-brain stem
人星形胶质细胞- 中脑	1850	HA-mb	Human Astrocytes-midbrain
人视网膜星形胶质细胞	1870	HRA	Human Retinal Astrocytes
人小神经胶质细胞	1900	HM	Human Microglia
大鼠细胞系统
中文名	货号	简称	英文名称
大鼠脑微血管内皮细胞	R1000	RBMEC	Rat Brain Microvascular Endothelial Cells
大鼠垂体细胞	R1200	RPC	Rat Pituitary Cells
大鼠脑膜细胞	R1400	RMC	Rat Meningeal Cells
大鼠脑脊神经元	R1510	RN-r	Rat Neurons-raphe
大鼠皮质神经元	R1520	RN-c	Rat Neurons-cortical
大鼠颗粒细胞	R1530	RGC	Rat Granule Cells
大鼠神经元- 海马	R1540	RN-h	Rat Neurons-hippocampal
大鼠黑质神经元	R1550	RN-sn	Rat Neurons-substantia nigra
大鼠纹状体神经元	R1560	RN-s	Rat Neurons-striatal
大鼠腹脊髓神经元	R1570	RN-vsc	Rat Neurons-ventral spinal cord
大鼠背脊髓神经元	R1580	RN-dsc	Rat Neurons-dorsal spinal cord
大鼠背脊髓神经元	R1590	RN-sc	Rat Neurons-spinal cord
大鼠少突胶质前体细胞	R1600	ROPC	Rat Oligodendrocyte Precursor Cells
大鼠雪旺细胞	R1700	RSC	Rat Schwann Cells
大鼠神经束膜成纤维细胞	R1710	RPNF	Rat Perineurial Fibroblasts
大鼠星形胶质细胞	R1800	RA	Rat Astrocytes
大鼠星形胶质细胞- 小脑	R1810	RA-c	Rat Astrocytes-cerebellar
大鼠星形胶质细胞- 海马	R1820	RA-h	Rat Astrocytes-hippocampal
大鼠小神经胶质细胞	R1900	RM	Rat Microglia
大鼠巨噬细胞	R1920	RMa	Rat Macrophage

 

 

近几年的新药研发成功率在逐年下降，其根本原因之一就是传统的药物筛选系统是建立在只具有30-40% 人类基因群的一系列细胞株上。这样一个有“缺陷型”药物筛选系统所产生的药物用于人体上就会出现许 多致命的弱点和不完整性。新一代药物筛选系统是含有一系列近乎完整的人类基因群的原代细胞株。而利 用这些原代细胞株所甄别和筛选出来的候选药物，其诊治人类疾病的成功几率将大大增加。这样不但大大 节省了新药的开发成本，而且将极大地提高人类的健康质量。这些产品从根本上提高了全球生命医学研究、 人类重要疾病药物研发、新药研发的成功率。 所以上海中乔新舟生物科技有限公司致力于提供优质原代细胞产品和完善的售后服务。 上海中乔新舟专长于为生物医药领域的医疗机构、研究中心、企业、临床医生等提供课题设计、基金联合申请、实验 技术服务、论文相关服务、采购外包等整体服务，目前已经成长为国内转化医学外包品牌。 中乔新舟的PI团队已经发展到专职PI 20人，联席PI 312人，其中大多数拥有海外背景。截止到2015年以PI或联席PI为 第一作者发表SCI 论文1682 篇（总IF 值为5721.82，其中影响因子IF>5.0 的论文216 篇，IF>10.0论文32 篇）。