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- 文献和实验
- 技术资料
- 英文名:
Saos-2
- 库存:
大量
- 供应商:
中乔新舟
- 细胞类型:
细胞系
- 相关疾病:
否
- 物种来源:
human
- 免疫类型:
否
- 细胞形态:
咨询销售
- 运输方式:
T25瓶运输
- 年限:
5-10年
- 生长状态:
贴壁生长
- 规格:
5 x 10^5 cells/vial
|
产品名称 |
Saos-2人成骨肉瘤细胞 |
|
货号 |
ZQ0447 |
|
产品介绍 |
Saos-2细胞是一种来源于一名11岁白人女性原发性成骨肉瘤的骨肉瘤细胞系。该病人曾经多种药物治疗,包括RTG.methotrexate,adriamycin vincristine,cytoxan和aramycin-C。该细胞在免疫抑制小鼠中不致瘤,但在半固体培养基中形成集落。该细胞是研究骨肉瘤和骨生物学广泛认可的模型,由于它们的成骨细胞特性和产生骨样细胞外基质的能力。 该细胞具有高水平的碱性磷酸酶活性和骨特异性蛋白(如骨钙素和骨桥蛋白)的表达,是研究骨形成和骨肉瘤病理生理的有效体外系统。它对于研究细胞对各种生化刺激和模拟骨环境的机械力的反应特别有价值。 注意事项: 建议用户仔细核对培养基配方和培养条件,每隔2-3天换液一次,并在细胞融合之前进行传代培养,使细胞处于好的培养条件。 |
|
种属 |
人 |
|
性别/年龄 |
女/11岁 |
|
组织 |
骨 |
|
疾病 |
骨肉瘤 |
|
细胞类型 |
肿瘤细胞 |
|
形态学 |
上皮的 |
|
生长方式 |
贴壁 |
|
倍增时间 |
大约35~48小时 |
|
培养基和添加剂 |
McCoy's 5A基础培养基(品牌:中乔新舟 货号:ZQ-1000)+15%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟 货号:CSP006) |
|
推荐完全培养基货号 |
ZM0447 |
|
生物安全等级 |
BSL-1 |
|
STR位点信息 |
Amelogenin: X CSF1PO: 10 D13S317: 12,13 D16S539: 12,13 D5S818: 12 D7S820: 8,10 THO1: 6,9 TPOX: 8 vWA: 18 |
|
培养条件 |
95%空气,5%二氧化碳;37℃ |
|
抗原表达/受体表达 |
*** |
|
基因表达 |
*** |
|
保藏机构 |
ATCC; CRL-7939 ATCC; HTB-85 DSMZ; ACC-243 ECACC; 89050205 |
|
供应限制 |
仅供科研使用 |
上海中乔新舟生物科技有限公司成立于2011年,历经十多年发展,主要专注于细胞生物学产品的研究和开发,专注于为药企、各类科研机构及CRO企业提供符合标准规范的细胞培养服务、细胞培养基、细胞检测试剂盒、细胞培养试剂,胎牛血清和细胞生物学技术服务等。
公司一直致力于为高等院校、研究机构、医院、CRO及CDMO企业提供细胞培养完整解决方案,这些产品旨在满足细胞培养的多样需求,确保实验和研究的有效进行。引用中乔新舟(ZQXZBIO)产品和服务的文献超数千篇。

产品服务
细胞资源:原代细胞、细胞株、干细胞、示踪细胞、耐药株细胞、永生化细胞等基因工程细胞。
试剂产品:胎牛血清、完全培养基(适用于原代细胞及细胞株)、无血清培养基、基础培养基、细胞转染试剂、重组因子、胰酶和双抗等等细胞培养所有实验相关产品。
技术服务:稳转株构建、原代细胞分离、特殊培养基定制服务、细胞检测等。

目前产品已经畅销国内30多个省市,与客户建立长期的合作伙伴关系,共同实现成功。全体员工将不懈努力,继续为科研人员提供优良的产品和服务,致力成为全球细胞培养领域的参与者。

企业愿景
致力于成为国内细胞培养基产业的佼佼者,生物医药领域上游原材料的优良提供商。
企业使命
成长为专业细胞系及原代细胞培养供应商、专业细胞培养基及培养试剂生产商。
企业荣誉


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文献和实验论文标题: Activation of CXCL6/CXCR1/2 Axis Promotes the Growth and Metastasis of Osteosarcoma Cells in vitro and in vivo
DOI: 10.3389/fphar.2019.00307
发表时间: 2019-03-28
期刊: Frontiers in Pharmacology
影响因子: 5.811
货号: ZQ0447
产品名称: SaOS-2 cell lines
论文标题: Knockdown of pyruvate kinase type M2 suppresses tumor survival and invasion in osteosarcoma cells both in vitro and in vivo
DOI: 10.1016/j.yexcr.2017.11.020
发表时间: 2017-11-16
期刊: EXPERIMENTAL CELL RESEARCH
影响因子: 3.905
货号: ZQ0447
产品名称: Saos-2 cells
论文标题: Circular RNA circVRK1 suppresses the proliferation, migration and invasion of osteosarcoma cells by regulating zinc finger protein ZNF652 expression via microRNA miR-337-3p
DOI: 10.1080/21655979.2021.1965695
发表时间: 2021-08-23
期刊: Bioengineered
影响因子: 3.269
货号: ZQ0447
产品名称: Saos-2 cells
论文标题: Paeonol antagonizes oncogenesis of osteosarcoma by inhibiting the function of TLR4/MAPK/NF-κB pathway
DOI: 10.1016/j.acthis.2019.151455
发表时间: 2019-10-03
期刊: ACTA HISTOCHEMICA
影响因子: 2.479
货号: ZQ0447
产品名称: Saos-2 cells
论文标题: Effect of lncRNA ANRIL knockdown on proliferation and cisplatin chemoresistance of osteosarcoma cells in vitro
DOI: 10.1016/j.prp.2019.01.042
发表时间: 2019-01-30
期刊: PATHOLOGY RESEARCH AND PRACTICE
影响因子: 1.794
货号: ZQ0447
产品名称: Saos-2 cells
论文标题: MicroRNA‑208a‑3p promotes osteosarcoma progression via targeting PTEN
DOI: 10.3892/etm.2020.9385
发表时间: 2020-10-23
期刊: Experimental and Therapeutic Medicine
影响因子: 1.785
货号: ZQ0447
产品名称: Saos-2 cells
论文标题: MicroRNA-506-3p initiates mesenchymal-to-epithelial transition and suppresses autophagy in osteosarcoma cells by directly targeting SPHK1
DOI: 10.1080/09168451.2019.1569496
发表时间: 2019-01-23
期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
影响因子: 1.297
货号: ZQ0447
产品名称: SaOS-2 cells
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