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产品名称：淀粉样肽前体蛋白抗体,Amyloid Precursor Protein
别 名：Secretory Amyloid Precursor Protein; Soluble APP-alpha; Soluble APP-beta; A4 amyloid protein; A4; AAA; ABETA; ABPP; AD 1; AD1; Alzheimer disease 1; Alzheimer disease; Alzheimer's disease amyloid protein; Amyloid beta (A4) precursor protein; Amyloid beta A4 protein; Amyloid beta A4 protein precursor isoform b; Amyloid beta A4 protein precursor isoform c; Amyloid beta A4 protein precursor isoform a; Amyloid beta A4 protein precursor isoform b; Amyloid beta A4 protein precursor isoform c; Amyloid beta protein; Amyloid beta-peptide; Amyloid of aging and alzheimer disease; APP; APP I; APPI; Beta amyloid peptide; Cerebral vascular amyloid peptide; CTFgamma; CVAP; Human mRNA for amyloid A4 precursor of Alzheimer's disease; PN 2; PN II; PN2; PreA4; Protease nexin II; A4_HUMAN.
研究领域：细胞生物 Alzheimer's
抗体来源：Mouse
克隆类型：Polyclonal
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用：WB=1:100-500 IHC-P=1:100-500 IHC-F=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量：72-83kDa
细胞定位：细胞核 细胞浆 细胞膜 细胞外基质
性 状：Lyophilized or Liquid
浓 度：1mg/1ml
免 疫 原：KLH conjugated synthetic peptide derived from the middle of human Soluble APP-beta/alpha
亚 型：IgG
纯化方法：affinity purified by Protein A
储 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
淀粉样肽前体蛋白抗体,Amyloid Precursor Protein相关产品：
HLA(sh-haling)031 大白鼠phospho-EIF4EBP1(Ser100) 磷酸化eIF4E结合蛋白抗体
HLA(sh-haling)032 大白鼠phospho-EIF4EBP1(Ser111) 磷酸化eIF4E结合蛋白抗体
HLA(sh-haling)033 大白鼠4EBP2 eIF4E结合蛋白2抗体
HLA(sh-haling)034 大白鼠EIF5 真核翻译起始因子5抗体
HLA(sh-haling)035 大白鼠5-HT 5-羟色胺抗体
HLA(sh-haling)036 大白鼠5-HTR1A 5-羟色胺受体1A抗体
HLA(sh-haling)037 大白鼠5-HTR1B 5-羟色胺受体1B抗体
HLA(sh-haling)038 大白鼠5-HTR2B 5-羟色胺受体2B抗体
HLA(sh-haling)039 大白鼠5-HTR2A 5-羟色胺受体2A抗体
HLA(sh-haling)040 大白鼠5-HTT 5-羟色胺转运蛋白抗体
HLA(sh-haling)041 大白鼠5-HTR3 5-羟色胺受体3抗体
HLA(sh-haling)042 大白鼠5-HTR4 5-羟色胺受体4抗体
HLA(sh-haling)043 大白鼠5 lipoxygenase/ALOX5 5-脂氧合酶抗体
HLA(sh-haling)044 大白鼠Phospho-5-Lipoxygenase(Ser271) 磷酸化5-脂氧合酶抗体
HLA(sh-haling)045 大白鼠Phospho-5-Lipoxygenase(Ser663) 磷酸化5-脂氧合酶抗体
HLA(sh-haling)046 大白鼠ALOX12/12 Lipoxygenase 12脂氧合酶抗体
HLA(sh-haling)047 大白鼠8-OHdG 8-羟基脱氧鸟苷抗体
HLA(sh-haling)048 大白鼠ADORA1 腺苷A1A受体抗体
HLA(sh-haling)049 大白鼠A2AR 腺苷A2A受体抗体
HLA(sh-haling)050 大白鼠AACT-Alpha1 α-1抗胰糜蛋白酶抗体
HLA(sh-haling)051 大白鼠AAK1 AP2关联激酶1抗体
HLA(sh-haling)052 大白鼠AANAT 芳香胺N-乙酰化转移酶抗体
HLA(sh-haling)053 大白鼠AARS2 丙氨酰tRNA合成酶2抗体
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文献和实验热病毒的人在遭遇不同品系病毒攻击时，第一次感染后产生的前体膜蛋白抗体会再次苏醒并发挥作用，但它们不但无法保护身体免受第二次感染，反而会帮助病毒进行复制，促使病毒感染更多的细胞。 研究人员称，前体膜蛋白抗体的这种行为解释了为什么第二次感染不同品系的登革热病毒会引起比首次感染更严重的损害。他们相信，如果登革热病毒疫苗含有这类前体膜蛋白抗体，就会引发类似问题，因此在设计新型登革热疫苗时，要避免这些抗体的出现。 研究论文的第一作者、伦敦帝国理工大学医学系主任加文·斯克里顿教授指出，目前全世界仍有很多人面临着登革
Interaction of the Presenilins with the Amyloid Precursor Protein (APP)
the deposition of amyloid Aβ peptide. The latter is released from its cognate amyloid precursor protein (APP) by a two-step proteolytic conversion: first, proteolysis of APP by β-secretase, which releases the N-terminus of Aβ, and second, conversion
Posttranslational Modifications of the Amyloid Precursor Protein: Glycosylation
Many studies have demonstrated the importance of amyloid precurser protein (APP) in the pathogenesis of Alzheimer’s disease. Nonetheless, the exact mechanism by which APP contributes to the pathogenesis of Alzheimer’s disease is still not clear
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