- 询价
- Cell Signaling Technology
- 5556
- USA
- 2025年11月01日
- W, IP
- Rabbit
- H,M,R,Mk
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- 详细信息
- 技术资料
- 抗体英文名：
DLST Antibody
- 抗原：
synthetic peptide corresponding to residues surrounding Val188 of human DLST protein
- 应用范围：
W, IP
- 宿主：
Rabbit
- 库存：
大量
- 适应物种：
H,M,R,Mk
- 保质期：
详见说明书
- 级别：
详见MSDS文件
- 供应商：
CST
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IP=Immunoprecipitation
Reactivity Key: H=Human M=Mouse R=Rat Mk=Monkey
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W IP | H M R Mk | Endogenous | 50 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | DLST Antibody detects endogenous levels of total DLST protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val188 of human DLST protein. Antibodies are purified by protein A and peptide affinity chromatography. Western Blotting
Western blot analysis of extracts from various cell lines using DLST Antibody. |
| Background | α-ketoglutarate dehydrogenase complex is a rate-regulating enzyme in the Krebs Cycle in mitochondria (1). Dihydrolipoamide succinyltransferase (DLST) is a key subunit in this complex (2). Mutations in the DLST gene may be responsible for the familial Alzheimer disease (1). Reduction of DLST increases the generation of reactive oxygen species production suggesting its role in oxidative stress (2). Deficiency of DLST in mice was suggested to cause increased oxidative stress in mitochondria and is involved in the pathogenesis of Alzheimer disease (2). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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