Pyk2 (H364) Antibody

Pyk2 (H364) Antibody

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年07月14日
  • W, IP
  • Rabbit
  • H,M
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    • 详细信息
    • 技术资料
    • 抗体英文名

      Pyk2 (H364) Antibody

    • 抗原

      synthetic peptide corresponding to residues surrounding His364 of human Pyk2

    • 应用范围

      W, IP

    • 宿主

      Rabbit

    • 供应商

      CST

    • 适应物种

      H,M

    • 级别

      详见MSDS文件

    • 保质期

      详见说明书

    • 库存

      大量

    • 是否单克隆

      2

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting  IP=Immunoprecipitation
    Reactivity Key:  H=Human  M=Mouse
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Source
    W IP H M Endogenous 116 Rabbit
    Protocols
    Specificity / Sensitivity

    Pyk2 (H364) Antibody detects endogenous levels of total Pyk2 protein. This antibody does not cross-react with other related proteins.

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His364 of human Pyk2. Antibodies are purified by protein A and peptide affinity chromatography.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from Jurkat and Ramos cells using Pyk2 (H364) Antibody.

    Background

    Protein tyrosine kinase Pyk2, also called CAKβ, RAFTK and CADTK, is a nonreceptor tyrosine kinase structurally related to focal adhesion kinase (FAK) (1-4). Pyk2 is predominantly expressed in cells derived from hematopoietic lineages and in the central nervous system. Pyk2 is one of the signaling mediators for the G-protein-coupled receptors and MAP kinase signaling pathway. It plays an important role in cell spreading and migration (5-7).

    1. Avraham, S. et al. (1995) J. Biol. Chem. 270, 27742-27751.
    2. Lev, S. et al. (1995) Nature 376, 737-745.
    3. Sasaki, H. et al. (1995) J. Biol. Chem. 270, 21206-21219.
    4. Yu, H. et al. (1996) J. Biol. Chem. 271, 29993-29998.
    5. Duong, L. T. et al. (2001) J. Biol. Chem. 276, 7484-7492.
    6. Watson, J. M. et al. (2001) J. Biol. Chem. 276, 3536-3542.
    7. Tang, H. et al. (2002) J. Biol. Chem. 277, 5441-5447.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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