- 询价
- R&D
- 美国/中国
- xy-39400
- 2025年07月14日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 技术资料
- 形态：
液态/粉状
- 保存条件：
-20℃保存
- 克隆性：
多克隆
- 标记物：
见说明书
- 适应物种：
人，大鼠，小鼠，兔
- 宿主：
Goat，Rabbit，Mouse
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 靶点：
来电咨询
- Ubiquitin (5-25) Monoclonal Antibody (SIGNET)详细信息：
-
Description 
Monoclonal Antibody against Ubiquitin (5-25)
(Formerly Signet Catalog Nos: 9400-02, 9400-05, 9400-10)Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone 5-25 Form Ascites Host Ubiquitin (5-25) Monoclonal Antibody (SIGNET)Mouse IsoType IgG1, kappa Specificity This antibody detects ubiquitin and ubiquitinated paired helical filaments (PHF). It is specific for residues 64-76 of ubiquitin and recognizes free and bound ubiquitin, and native or detergent extracted PHF. Formalin fixation eliminates immunoreactivity. Uses This antibody is effective in immunoblotting, immunohistochemistry (IHC) on unfixed tissues, immunopurification (IP) and ELISA. Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. - Western blot: 1:1,000
- IHC: 1:1,000
- IP: 1:100 - 1:1,000
- ELISA: 1:1,000 - 1:10,000
Storage Store at -20°C or below. Upon initial thawing, apportion into working aliquots and store at -20°C or below. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. Do not store in frost-free freezers. References Ubiquitin (5-25) Monoclonal Antibody (SIGNET)Ping G, Khatoon S, Iqbal K, Grundke-Iqbal I. Brain ubiquitin is markedly elevated in Alzheimer’s disease. Brain Res. 566:146-151, 1991.
Perry G, Mulvhill P, Fried VA, Smith HT, Grundke-Iqbal I, Iqbal K. Immunochemical properties of ubiquitin conjugated in the paired helical filaments of Alzheimer’s disease. J. Neurochem. 52:1523- 1528, 1989.
Grundke-Iqbal I, Iqbal K, Quinlan M, Tung YC, Zaidi M, Wisniewski HM. Microtubule-associated protein tau, a component of Alzheimer paired helical filaments. J. Biol. Chem. 261:6084-6089, 1986.
Grundke-Iqbal I, Wang GP, Iqbal K, Tung YC, Wisniewski HM. Alzheimer paired helical filaments: Identification of polypeptides with monoclonal antibodies. Acta. Neuropathol. 68:279-283, 1985.
Wang GP, Grundke-Iqbal, Kascsak RJ, Iqbal K, Wisniewski HM. Alzheimer neurofibrillary tangles: Monoclonal antibodies to inherent antigen(s). Acta. Neuropathol. 62:268-275, 1984.Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - Ubiquitin (5-25) Monoclonal Antibody (SIGNET)
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Ubiquitin (5-25) Monoclonal Antibody (SIGNET)
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