- 询价
- R&D
- 美国/中国
- xy-39500
- 2025年07月15日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 技术资料
- 形态：
液态/粉状
- 保存条件：
-20℃保存
- 克隆性：
多克隆
- 标记物：
见说明书
- 适应物种：
人，大鼠，小鼠，兔
- 宿主：
Goat，Rabbit，Mouse
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 靶点：
来电咨询
- Ubiquitin (3-39) Monoclonal Antibody (SIGNET)详细信息：
-
Description 
Monoclonal Antibody against Ubiquitin (3-39)
(Formerly Signet Catalog Nos: 9500-02, 9500-05, 9500-10)Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone 3-39 Form Ascites Host Mouse IsoType IgG1, kappa [Ab] Ubiquitin (3-39) Monoclonal Antibody (SIGNET)~2 mg/mL Specificity This antibody detects ubiquitinated proteins. It is specific for residues 50-65 of ubiquitin and recognizes ubiquitinated protein, but not free ubiquitin. Clone 3-39 can be used on native or detergent extracted formalin fixed tissues and the epitope is resistant to proteolytic enzyme treatment. Uses This antibody is effective in immunoblotting, immunohistochemistry (IHC) on unfixed tissues, immunoprecipitation (IP) and ELISA. Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. - Western blot: 1:1,000
- IHC: 1:100 - 1:1,000
- IP: 1:100
- ELISA: 1:10,000
Storage Store at -20°C or below. Upon initial thawing, apportion into working aliquots and store at -20°C or below. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. Do not store in frost-free freezers. References Ubiquitin (3-39) Monoclonal Antibody (SIGNET)Wang GP, Khatoon S, Iqbal K, Grundke-Iqbal I. Brain ubiquitin is markedly elevated in Alzheimer’s disease. Brain Res 566:146- 151, 1991.
Wang GP, Iqbal K, Bucht G, Winblad B, Wisniewski HM, Grundke- Iqbal I. Alzheimer’s disease: paired helical filament immunoreactivity in cerebrospinal fluid. Acta Neuropathol 82:6-12, 1991.
Perry G, Mulvhill P, Fried VA, Smith HT, Grundke-Iqbal I, Iqbal K. Immunochemical properties of ubiquitin conjugated in the paired helical filaments of Alzheimer’s disease. J Neurochem 52:1523- 1528, 1989.
Galloway PG, Grundke-Iqbal I, Iqbal K, Perry G. Lewy bodies contain epitopes both shared and distinct from Alzheimer neurofibrillary tangles. J Neuropath Exper Neurol 47:654-663, 1988.
Grundke-Iqbal I, Iqbal K, Quinlan M, Tung YC, Zaidi M, Wisniewski HM. Microtubule-associated protein tau, a component of Alzheimer paired helical filaments. J Biol Chem 261:6084-6089, 1986.
Grundke-Iqbal I, Wang GP, Iqbal K, Tung YC, Wisniewski HM. Alzheimer paired helical filaments: Identification of polypeptides with monoclonal antibodies. Acta Neuropathol 68:279-283, 1985.
Wang GP, Grundke-Iqbal, Kascsak RJ, Iqbal K, Wisniewski HM. Alzheimer neurofibrillary tangles: Monoclonal antibodies to inherent antigen(s). Acta Neuropathol 62:268-275, 1984.Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - Ubiquitin (3-39) Monoclonal Antibody (SIGNET)
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Ubiquitin (3-39) Monoclonal Antibody (SIGNET)
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