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Human EIF4E

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  • ¥1200 - 19200
  • SinoBio
  • 国产
  • CH36
  • 2025年10月29日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Met1-Val217

    • 保质期

      See instructions

    • 英文名

      标签:Tag free

    • 库存

      表达系统:E.coli

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1200.0
    规格:50ug产品价格:¥3520.0
    规格:500ug产品价格:¥12320.0
    规格:1mg产品价格:¥19200.0
    产品描述
    Recombinant Human Eukaryotic Translation Initiation Factor 4E is produced by our E.coli expression system and the target gene encoding Met1-Val217 is expressed.
    蛋白编号
    AAH12611.1
    产品别称
    Eukaryotic translation initiation factor 4E; eIF-4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein; EIF4E; EIF4EL1; EIF4F
    偶联
    Unconjugated
    分子量
    25.1 KDa
    表观分子量
    25 KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 6% Trehalose, 0.05% Tween80, pH8.0.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20℃, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8℃ for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20℃ for 3 months.
    产品背景
    Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners.It can recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

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    图标文献和实验
    该产品被引用文献

    Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners.It can recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

    相关实验
    • Adv Sci:林戈/薛愿超合作阐明 eIF4E1B 在哺乳动物卵母细胞向胚胎转换过程中母源 mRNA 选择性翻译的作用机制

      2023 年 2 月 8 日,中南大学/中信湘雅生殖与遗传医院林戈教授团队联合中科院生物物理所薛愿超实验室在 Advanced Science 杂志上在线发表了题为 Selective Translation of Maternal mRNA by eIF4E1B Controls Oocyte to Embryo Transition 的研究论文,首次报道了卵母细胞内特异的翻译起始因子 eIF4E1B 在哺乳动物卵母细胞向胚胎转换过程中的生理功能,同时也提出在卵母细胞中存在的特异翻译激活模型

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    Human EIF4E
    ¥1200 - 19200