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Human ICAM-2

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  • ¥400 - 17600
  • SinoBio
  • 国产
  • C306
  • 2025年11月01日
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    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Lys25-Gln223

    • 保质期

      See instructions

    • 英文名

      标签:C-6His

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥400.0
    规格:50ug产品价格:¥1200.0
    规格:500ug产品价格:¥12320.0
    规格:1mg产品价格:¥17600.0
    产品描述
    Recombinant Human Intercellular Adhesion Molecule 2 is produced by our Mammalian expression system and the target gene encoding Lys25-Gln223 is expressed with a 6His tag at the C-terminus.
    蛋白编号
    P13598
    产品别称
    Intercellular Adhesion Molecule 2; ICAM-2; CD102; ICAM2
    偶联
    Unconjugated
    分子量
    23.13 KDa
    表观分子量
    40-60 KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    产品背景
    ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.

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    图标文献和实验
    该产品被引用文献

    ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.

    相关实验
    • Purification of ICAM-1

        Purpose The purification of ICAM-1 on R6.5 anti-ICAM-1 column. Materials Triethylamine NaCl Octyl Glucoside ( n-octyl-b -D-glucopyranoside Sigma Cat. No. O-8001) Tris-Base NaN3 Tris-HCl

    • ICAM-1纯化 Purification of ICAM-1

          Purification of ICAM-1 by Mazen Ferzly, 06/22/2000 Purpose The purification of ICAM-1 on R6.5 anti-ICAM-1 column. Materials Triethylamine NaCl Octyl Glucoside ( n-octyl-b -D-glucopyranoside Sigma Cat

    • ELISA FOR DETECTING SECRETED ICAM-1

      substrate and substrate buffer (Zymed; #00-2011) ABTS chromogen solution Hydrogen Peroxidase solution Citrate buffer Anti-ICAM-1 mAb R6.5 or CL203. Use as 10 ug/ml in PBS to coat plates. Biotinylated mAb

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    文献支持
    Human ICAM-2
    ¥400 - 17600