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Human IL-4(C050)

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  • ¥936 - 14080
  • SinoBio
  • 国产
  • C050
  • 2025年11月08日
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    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:His25-Ser153

    • 保质期

      See instructions

    • 英文名

      标签:Tag free

    • 库存

      表达系统:E.coli

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥936.0
    规格:50ug产品价格:¥2800.0
    规格:500ug产品价格:¥9840.0
    规格:1mg产品价格:¥14080.0
    产品描述
    Recombinant Human Interleukin-4 is produced by our E.coli expression system and the target gene encoding His25-Ser153 is expressed.
    蛋白编号
    P05112
    产品别称
    Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4
    分子量
    15.1 KDa
    表观分子量
    13-14 KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.2.
    内毒素
    < 0.01 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    纯度-SEC-HPLC
    Greater than 95% as determined by SEC-HPLC. (Regularly tested)
    生物活性-Cell Based Assay
    Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 10-70 pg/ml. (QC verified)
    生物活性-BLI
    Loaded Cynomolgus IL-4RA-Fc(Cat#C939) on Protein A Biosensor, can bind Human IL-4(Cat#C050) with an affinity constant of <10-3 nM as determined in BLI assay. (Regularly tested)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    产品背景
    Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.

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    图标文献和实验
    该产品被引用文献

    Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.

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    文献支持
    Human IL-4(C050)
    ¥936 - 14080