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- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
Room Temperature
- 保质期：
1年
- 英文名：
Heparin sodium salt
- 库存：
100⁺瓶
- 供应商：
上海睿安生物13611631389
- CAS号：
9041-08-1
- 规格：
25KU/瓶
Sigma货号H3149肝素钠盐(Heparin sodium salt)上海睿安生物13611631389
肝素 钠盐 来源于猪肠粘膜
Grade I-A,≥180 USP units/mg,powder,BioReagent,suitable for cell culture
说明
一般描述
肝素主要用于推迟血液的凝固。它在凝血途径中可增强抗凝血酶介导的蛋白酶失活。
肝素钠是一种来自糖胺聚糖家族的硫酸化多糖，在细胞培养、癌症生物学和药物发现研究中发挥着至关重要的作用。它对蛋白质和细胞相互作用的影响使其对于研究分子和细胞过程、肿瘤建模、探索结合相互作用以及作为支持细胞活力的细胞培养补充剂很有价值。
应用
- 来自猪肠粘膜的肝素钠盐已用于从人血浆中纯化sLRP（可溶性循环低密度脂蛋白受体相关蛋白-1）。
- 它已被用作用于培养人脐静脉内皮细胞的M199培养基中的一种补充剂。
- 它在血液分离的过程中被用作抗凝血剂。
特点和优势:高纯度化合物适用于各种研究应用
同行评审论文(部分文献)
Exosomes isolated from cancer patients' sera transfer malignant traits and confer the same phenotype of primary tumors to oncosuppressor-mutated cells.
Mohamed Abdouh et al.
Journal of experimental & clinical cancer research : CR, 36(1), 113-113 (2017-09-01)
Horizontal transfer of malignant traits from the primary tumor to distant organs, through blood circulating factors, has recently become a thoroughly studied metastatic pathway to explain cancer dissemination. Recently, we reported that oncosuppressor gene-mutated human cells undergo malignant transformation when
Factor Xa and thrombin, but not factor VIIa, elicit specific cellular responses in dermal fibroblasts.
Bachli EB et al.
Journal of Thrombosis and Haemostasis, 1, 1935-1935 (2003)
Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-? is an early biomarker for mild cognitive impairment preceding Alzheimer's disease.
Sagare AP et al.
Journal of Alzheimer'S Disease, 24, 25-25 (2011)
Determinants of Zika virus host tropism uncovered by deep mutational scanning.
Yin Xiang Setoh et al.
Nature microbiology, 4(5), 876-887 (2019-03-20)
Arboviruses cycle between, and replicate in, both invertebrate and vertebrate hosts, which for Zika virus (ZIKV) involves Aedes mosquitoes and primates1. The viral determinants required for replication in such obligate hosts are under strong purifying selection during natural virus evolution
Mapping of histone-binding sites in histone replacement-completed spermatozoa.
Keisuke Yoshida et al.
Nature communications, 9(1), 3885-3885 (2018-09-27)
The majority of histones are replaced by protamines during spermatogenesis, but small amounts are retained in mammalian spermatozoa. Since nucleosomes in spermatozoa influence epigenetic inheritance, it is important to know how histones are distributed in the sperm genome. Conflicting data
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文献和实验该产品被引用文献
Sigma货号H3149肝素钠盐(Heparin sodium salt)上海睿安生物13611631389
肝素 钠盐 来源于猪肠粘膜
Grade I-A,≥180 USP units/mg,powder,BioReagent,suitable for cell culture
说明
一般描述
肝素主要用于推迟血液的凝固。它在凝血途径中可增强抗凝血酶介导的蛋白酶失活。
肝素钠是一种来自糖胺聚糖家族的硫酸化多糖，在细胞培养、癌症生物学和药物发现研究中发挥着至关重要的作用。它对蛋白质和细胞相互作用的影响使其对于研究分子和细胞过程、肿瘤建模、探索结合相互作用以及作为支持细胞活力的细胞培养补充剂很有价值。
应用
- 来自猪肠粘膜的肝素钠盐已用于从人血浆中纯化sLRP（可溶性循环低密度脂蛋白受体相关蛋白-1）。
- 它已被用作用于培养人脐静脉内皮细胞的M199培养基中的一种补充剂。
- 它在血液分离的过程中被用作抗凝血剂。
特点和优势:高纯度化合物适用于各种研究应用
同行评审论文(部分文献)
Exosomes isolated from cancer patients' sera transfer malignant traits and confer the same phenotype of primary tumors to oncosuppressor-mutated cells.
Mohamed Abdouh et al.
Journal of experimental & clinical cancer research : CR, 36(1), 113-113 (2017-09-01)
Horizontal transfer of malignant traits from the primary tumor to distant organs, through blood circulating factors, has recently become a thoroughly studied metastatic pathway to explain cancer dissemination. Recently, we reported that oncosuppressor gene-mutated human cells undergo malignant transformation when
Factor Xa and thrombin, but not factor VIIa, elicit specific cellular responses in dermal fibroblasts.
Bachli EB et al.
Journal of Thrombosis and Haemostasis, 1, 1935-1935 (2003)
Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-? is an early biomarker for mild cognitive impairment preceding Alzheimer's disease.
Sagare AP et al.
Journal of Alzheimer'S Disease, 24, 25-25 (2011)
Determinants of Zika virus host tropism uncovered by deep mutational scanning.
Yin Xiang Setoh et al.
Nature microbiology, 4(5), 876-887 (2019-03-20)
Arboviruses cycle between, and replicate in, both invertebrate and vertebrate hosts, which for Zika virus (ZIKV) involves Aedes mosquitoes and primates1. The viral determinants required for replication in such obligate hosts are under strong purifying selection during natural virus evolution
Mapping of histone-binding sites in histone replacement-completed spermatozoa.
Keisuke Yoshida et al.
Nature communications, 9(1), 3885-3885 (2018-09-27)
The majority of histones are replaced by protamines during spermatogenesis, but small amounts are retained in mammalian spermatozoa. Since nucleosomes in spermatozoa influence epigenetic inheritance, it is important to know how histones are distributed in the sperm genome. Conflicting data
相关实验
Procedures for In Vitro Production of Bovine Embryos
4263) Gentamicin (G1397) L-Glutamine (G5763) Heparin, sodium salt (H3149) HEPES (H4034) Hyaluronidase (H3884) � an embryo-tested, more expensive product is also available (H4272) Hypotaurine (H1348) Magnesium chloride
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Sigma货号H3149肝素钠盐(Heparin sodium salt)上海睿安生物13611631389
￥944.27
